Last updated on October 2017

A Study of Biomarker-Driven Therapy in Metastatic Colorectal Cancer (mCRC)


Brief description of study

This randomized, multi-center, active-controlled, open-label, parallel-group study will investigate the efficacy and safety of biomarker-driven maintenance treatment for first-line mCRC. Participants with mCRC are eligible for entry and cannot have received any prior chemotherapy in the metastatic setting. The entire study duration is anticipated to be approximately 7.5 years.

Clinical Study Identifier: NCT02291289

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Reference Study ID Number: MO29112 ...

Centre Anti Cancer Beau-fraisier;Service d'oncologie m dicale
Algiers, Algeria
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CHU Oran; Service d'Oncologie M dicale
Oran, Algeria
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EHS Oncologie Emir Abdelkader Oran; Service d'Oncologie M dicale
Oran, Algeria
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Reference Study ID Number: MO29112 ...

CHU de Tizi Ouzou; Service d'Oncologie M dicale
Tizi Ouzou, Algeria
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Reference Study ID Number: MO29112 ...

Hospital de Gastroenterologia Dr. Bonorino Udaondo ; Servicio de Oncolog a
Buenos Aires, Argentina
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Centro Oncologico Riojano Integral (CORI)
La Rioja, Argentina
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Cl nica Viedma
Viedma, Rio Negro, Argentina
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Reference Study ID Number: MO29112 ...

Institut Jules Bordet X
Brussels, Belgium
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Reference Study ID Number: MO29112 ...

Clin Univ de Bxl H pital Erasme
Bruxelles, Belgium
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UZ Leuven Gasthuisberg
Leuven, Belgium
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Clinique Saint-Joseph
Liège, Belgium
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AZ Delta (Campus Wilgenstraat)
Roeselare, Belgium
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Reference Study ID Number: MO29112 ...

University Clinical Center of the Republic of Srpska
Banja Luka, Bosnia and Herzegovina
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Clinic of Oncology, University Clinical Center Sarajevo
Sarajevo, Bosnia and Herzegovina
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Reference Study ID Number: MO29112 ...

Clinicas Oncologicas Integradas - COI
Rio De Janeiro, Brazil
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CITO - Centro Integrado de Terapia Onco-Hematol gica - Hospital da Cidade de Passo Fundo
Passo Fundo, Brazil
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Hospital das Clinicas - UFRGS
Porto Alegre, Brazil
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Hospital Sao Lucas - PUCRS
Porto Alegre, Brazil
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Hospital Nossa Senhora da Conceicao
Porto Alegre, Brazil
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Hospital de Cancer de Barretos
Barretos, Brazil
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Hospital Amaral Carvalho
Jau, Brazil
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Hospital de Base de Sao Jose do Rio Preto
Sao Jose do Rio Preto, Brazil
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Instituto de Ensino e Pesquisa Sao Lucas - IEP
Sao Paulo, Brazil
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Instituto do Cancer do Estado de Sao Paulo - ICESP
Sao Paulo, Brazil
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Bank of Cyprus Oncology Center
Nicosia, Cyprus
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Herlev Hospital; Onkologisk afdeling
Herlev, Denmark
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Regionshospitalet Herning; Onkologisk afdeling
Herning, Denmark
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Hiller d Sygehus; Medicinsk Enhed 1, 0862
Hillerod, Denmark
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Rigshospitalet, Onkologisk Klinik
København Ø, Denmark
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Odense Universitetshospital, Onkologisk Afdeling R
Odense, Denmark
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Sygehus Syd Roskilde; Onkologisk/haematologisk ambulatorium
Roskilde, Denmark
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Cancer Epidemiology Research Cluster; Clinical Cancer Department
Alexandria, Egypt
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National Cancer Institute
Cairo, Egypt
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Ain Shams University Hospital; Oncology
Cairo, Egypt
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Clinique Sainte Catherine
Avignon, France
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HOPITAL JEAN MINJOZ; Oncologie
Besancon, France
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Hopital Augustin Morvan; Federation De Cancerologie
Brest, France
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Chu Estaing; Chir Generale Digestive A Et B
Clermont Ferrand, France
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Institut Hospitalier Franco-Britannique; Cancerologie
Levallois-Perret, France
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Hopital Claude Huriez; Medecine Interne Oncologie
Lille, France
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Ch De Montbeliard;Chir Generale Digestive
Montbeliard, France
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Hopital Caremeau; Gastro Enterologie
Nimes, France
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Hopital Saint Antoine; Oncologie Medicale
Paris, France
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Hopital Haut Leveque
Pessac, France
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Chu La Miletrie; Gastro Enterologie Endoscopies
Poitiers, France
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Centre Paul Strauss; Oncologie Medicale
Strasbourg, France
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Hopital Rangueil; Gastro Enterologie Et Nutrition
Toulouse, France
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Institut Gustave Roussy; Departement Oncologie Medicale
Villejuif, France
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H matologisch-onkologische Praxis Dr. med. - Brudler, - Heinrich, - Bangerter
Augsburg, Germany
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Charit -Universit tsm. Berlin; Med. Klinik mit Schwerpunkt H matologie, Onkologie und Tumorimmunolo.
Berlin, Germany
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Onkologische Schwerpunktpraxis Kurf rstendamm
Berlin, Germany
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DRK Kliniken Berlin K penick Darmzentrum
Berlin, Germany
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Onkologische Gemeinschaftspraxis
Dresden, Germany
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Reference Study ID Number: MO29112 ...

Krankenhaus Nordwest; Klinik f. Onkologie und H matologie
Frankfurt, Germany
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Reference Study ID Number: MO29112 ...

PIOH PD Dr. R. Schnell - Dr. H. Schulz - Dr. M. Hellmann
Frechen, Germany
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Klinik Fulda, Medizinisches Versorgungszentrum Osthessen GmbH
Fulda, Germany
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Universit tsklinikum Hamburg-Eppendorf, Onkologisches Zentrum, Studienzentrale der II. Med. Klinik
Hamburg, Germany
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Medizinische Hochschule; Zentrum Innere Medizin; Abt. H matologie u. Onkologie
Hannover, Germany
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Reference Study ID Number: MO29112 ...

SLK-Kliniken Heilbronn GmbH Klinik f r Innere Medizin III, Onkologisches Studienzentrum
Heilbronn, Germany
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Klinik der Ruhr-Uni Bochum; Marien-Hospital Herne
Herne, Germany
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Gemeinschaftspraxis; Onkologisches Zentrum Lebach; Caritas Krankenhaus Lebach
Lebach, Germany
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Onkologische Gemeinschaftspraxis
Magdeburg, Germany
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Universit tsklinikum Magdeburg, Klinik f r Allgemein-, Viszeral- u. Gef chirurgie
Magdeburg, Germany
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Klinikum Magdeburg gGmbH Klinik f r Allgemein- und Viszeralchirurgie
Magdeburg, Germany
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Kliniken Maria Hilf GmbH, Krankenhaus St. Franziskus
Mönchengladbach, Germany
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St dt. Klinikum M nchen GmbH Klinikum Neuperlach Klinik f.H matologie u.Onkologie
München, Germany
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Gemeinschaftspraxis f r H matologie und Onkologie
Münster, Germany
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Reference Study ID Number: MO29112 ...

Br derkrankenhaus St. Josef
Paderborn, Germany
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Reference Study ID Number: MO29112 ...

Studienzentrum Onkologie Ravensburg; Onkologie Ravensburg
Ravensburg, Germany
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Reference Study ID Number: MO29112 ...

Prosper-Hospital, Medizinische Klinik I
Recklinghausen, Germany
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Reference Study ID Number: MO29112 ...

Krankenhaus Barmherziger Br der; Klinik f r Internistische Onkologie / H matologie
Regensburg, Germany
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Reference Study ID Number: MO29112 ...

Klinikum am Steinenberg / Ermstalklinik
Reutlingen, Germany
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Reference Study ID Number: MO29112 ...

Praxis F r Haematologie & Onkologie
Saarbruecken, Germany
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Reference Study ID Number: MO29112 ...

MVZ f r H matologie, Onkologie, Strahlentherapie und Palliativmedizin -; Klinik Dr. Hancken
Stade, Germany
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Reference Study ID Number: MO29112 ...

Klinikum Mutterhaus der Borromaeerinnen gGmbH; Haematologie/Onkologie
Trier, Germany
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Reference Study ID Number: MO29112 ...

Klinikum Wetzlar-Braunfels, Klinik f r H matologie/Onkologie und Palliativmedizin
Wetzlar, Germany
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Reference Study ID Number: MO29112 ...

Universit tsklinikum W rzburg; Medizinische Klinik und Poliklinik II; H matologie / Onkologie
Würzburg, Germany
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Reference Study ID Number: MO29112 ...

Agioi Anargyroi; 3Rd Dept. of Medical Oncology
Athens, Greece
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Reference Study ID Number: MO29112 ...

Univ General Hosp Heraklion; Medical Oncology
Heraklion, Greece
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Reference Study ID Number: MO29112 ...

Uni Hospital of Ioannina; Oncology Dept.
Ioannina, Greece
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Reference Study ID Number: MO29112 ...

University Hospital of Patras Medical Oncology
Patras, Greece
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Reference Study ID Number: MO29112 ...

Thermi Clinic; Oncology Clinic
Thermi Thessalonikis, Greece
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Reference Study ID Number: MO29112 ...

Bioclinic Thessaloniki
Thessaloniki, Greece
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Reference Study ID Number: MO29112 ...

IRCCS Istituto Nazionale Tumori Fondazione Pascale; Oncologia Medica A
Napoli, Italy
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Reference Study ID Number: MO29112 ...

IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica
Meldola, Italy
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Reference Study ID Number: MO29112 ...

A.O. Universitaria Di Parma; Oncologia Medica
Parma, Italy
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Reference Study ID Number: MO29112 ...

Istituto Regina Elena; Oncologia Medica A
Roma, Italy
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Reference Study ID Number: MO29112 ...

Policlinico Universitario "Agostino Gemelli"; U.O.C. Oncologia Medica
Roma, Italy
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Reference Study ID Number: MO29112 ...

Humanitas Gavazzeni;U.O. Oncologia Medica
Bergamo, Italy
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Reference Study ID Number: MO29112 ...

Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 1
Milano, Italy
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Reference Study ID Number: MO29112 ...

Irccs Istituto Europeo Di Oncologia (IEO); Oncologia Medica
Milano, Italy
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Reference Study ID Number: MO29112 ...

Asst Grande Ospedale Metropolitano Niguarda; Dipartimento Di Ematologia Ed Oncologia
Milano, Italy
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Reference Study ID Number: MO29112 ...

A.O. Citt della Salute e della Scienza - Presidio Molinette; divisione oncologia medica
Torino, Italy
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Reference Study ID Number: MO29112 ...

IRCCS Ospedale Casa Sollievo Della Sofferenza; Oncologia
San Giovanni Rotondo, Italy
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Reference Study ID Number: MO29112 ...

Azienda Ospedaliero-Universitaria Careggi;S.C. Oncologia Medica 1
Firenze, Italy
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Reference Study ID Number: MO29112 ...

IRCCS Istituto Oncologico Veneto (IOV); Oncologia Medica Prima
Padova, Italy
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Reference Study ID Number: MO29112 ...

A.O.U.I. VERONA-OSPEDALE POLICLINICO G.B. ROSSI BORGO ROMA;ONCOLOGIA MEDICA-d.U.
Verona, Italy
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Reference Study ID Number: MO29112 ...

Seoul National University Hospital
Seoul, Korea, Republic of
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Reference Study ID Number: MO29112 ...

Severance Hospital, Yonsei University Health System
Seoul, Korea, Republic of
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Reference Study ID Number: MO29112 ...

Asan Medical Center
Seoul, Korea, Republic of
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Reference Study ID Number: MO29112 ...

Samsung Medical Center
Seoul, Korea, Republic of
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Reference Study ID Number: MO29112 ...

Instituto Nacional de Cancerologia; Oncology
Distrito Federal, Mexico
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Reference Study ID Number: MO29112 ...

Fundacion Rodolfo Padilla Padilla A.C.
León, Mexico
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Reference Study ID Number: MO29112 ...

Oaxaca Site Management Organization
Oaxaca, Mexico
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Reference Study ID Number: MO29112 ...

Cancerologia de Queretaro; Oncologia
Queretaro, Queretaro, Mexico
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Reference Study ID Number: MO29112 ...

Antoni van Leeuwenhoek Ziekenhuis
Amsterdam, Netherlands
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Reference Study ID Number: MO29112 ...

Academisch Medisch Centrum Universiteit Amsterdam
Amsterdam, Netherlands
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Reference Study ID Number: MO29112 ...

Ijsselland Ziekenhuis; Inwendige Geneeskunde
Capelle a/d IJssel, Netherlands
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Reference Study ID Number: MO29112 ...

Deventer Ziekenhuis; Interne Geneeskunde
Deventer, Netherlands
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Reference Study ID Number: MO29112 ...

Albert Schweitzer Ziekenhuis; Inwendige Geneeskunde
Dordrecht, Netherlands
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Reference Study ID Number: MO29112 ...

Catharina ZKHS; Inwendige Geneeskunde Afd.
Eindhoven, Netherlands
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Reference Study ID Number: MO29112 ...

UMC St Radboud; Interne Oncologie; Medical Oncology Department
Nijmegen, Netherlands
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Reference Study ID Number: MO29112 ...

St. Antonius locatie Leidsche Rijn
Utrecht, Netherlands
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Isala Klinieken
Zwolle, Netherlands
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Szpital Uniwersytecki w Krakowie, Oddzia Kliniczny Kliniki Onkologii
Krakow, Poland
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Centrum Onkologii - Instytut im. M. Sklodowskiej-Curie; Klinika Gastroenterologii Onkologicznej
Warszawa, Poland
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Reference Study ID Number: MO29112 ...

HUC; Servico de Oncologia Medica
Coimbra, Portugal
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Centro Clinico Champalimaud; Oncologia Medica
Lisboa, Portugal
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Reference Study ID Number: MO29112 ...

Hospital de Santa Maria; Servico de Oncologia Medica
Lisboa, Portugal
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Russian Oncology Research Center n.a. N.N. Blokhin Dpt of Clinical Pharmacology and Chemotherapy
Moscow, Russian Federation
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Reference Study ID Number: MO29112 ...

P.A. Herzen Oncological Inst. ; Oncology
Moscow, Russian Federation
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Reference Study ID Number: MO29112 ...

First Pavlov State Medical University of St.Petersburg
Saint-Petersburg, Russian Federation
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Reference Study ID Number: MO29112 ...

S-Pb clinical scientific practical center of specialized kinds of medical care (oncological)
Saint-Petersburg, Russian Federation
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Reference Study ID Number: MO29112 ...

Bashkirian Republican Clinical Oncology Dispensary
UFA, Russian Federation
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Reference Study ID Number: MO29112 ...

Institute for Oncology and Radiology of Serbia; Medical Oncology
Belgrade, Serbia
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Reference Study ID Number: MO29112 ...

Clinical Center Bezanijska Kosa
Belgrade, Serbia
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Reference Study ID Number: MO29112 ...

Oncology Institute of Vojvodina
Sremska Kamenica, Serbia
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Reference Study ID Number: MO29112 ...

Onkologicky ustav sv. Alzbety, s.r.o.
Bratislava, Slovakia
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Reference Study ID Number: MO29112 ...

Narodny Onkologicky Ustav; Oddelenie klinickej onkologie E
Bratislava, Slovakia
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Reference Study ID Number: MO29112 ...

POKO Poprad; Department of Oncology
Poprad, Slovakia
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Reference Study ID Number: MO29112 ...

Institute of Oncology Ljubljana
Ljubljana, Slovenia
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Reference Study ID Number: MO29112 ...

Hospital General Universitario de Elche; Servicio de Oncologia
Elche, Spain
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Reference Study ID Number: MO29112 ...

Hospital Univ. Central de Asturias; Servicio de Oncologia
Oviedo, Spain
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Hospital Universitario Marques de Valdecilla; Servicio de Oncologia
Santander, Spain
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Hospital de Donostia; Servicio de Oncologia Medica
San Sebastian, Spain
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Reference Study ID Number: MO29112 ...

Hospital Universitario Son Espases
Palma De Mallorca, Spain
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Reference Study ID Number: MO29112 ...

Complejo Hospitalario Universitario de Santiago (CHUS) ; Servicio de Oncologia
Santiago de Compostela, Spain
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Complejo Hospitalario Nuestra Se ora de la Candelaria; Servicio de Oncologia
Santa Cruz de Tenerife, Spain
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Reference Study ID Number: MO29112 ...

Hospital de Cruces; Servicio de Oncologia
Barakaldo, Spain
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Reference Study ID Number: MO29112 ...

Hospital General Univ. de Alicante; Servicio de Oncologia
Alicante, Spain
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Reference Study ID Number: MO29112 ...

Hospital Univ Vall d'Hebron; Servicio de Oncologia
Barcelona, Spain
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Reference Study ID Number: MO29112 ...

Hospital Universitari Germans Trias i Pujol; Servicio de Oncologia
Barcelona, Spain
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Reference Study ID Number: MO29112 ...

Hospital Universitario Reina Sofia; Servicio de Oncologia
Cordoba, Spain
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Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico; Servicio de Oncologia
Jaen, Spain
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Hospital Universitari Arnau de Vilanova de Lleida; Servicio de Oncologia
Lerida, Spain
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Reference Study ID Number: MO29112 ...

Hospital General Universitario Gregorio Mara on; Servicio de Oncologia
Madrid, Spain
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Reference Study ID Number: MO29112 ...

Hospital Ramon y Cajal; Servicio de Oncologia
Madrid, Spain
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Reference Study ID Number: MO29112 ...

Hospital Universitario 12 de Octubre; Servicio de Oncologia
Madrid, Spain
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Reference Study ID Number: MO29112 ...

Hospital Universitario La Paz; Servicio de Oncologia
Madrid, Spain
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Reference Study ID Number: MO29112 ...

Hospital Universitario Puerta de Hierro; Servicio de Oncologia
Madrid, Spain
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Reference Study ID Number: MO29112 ...

Hospital Regional Universitario Carlos Haya; Servicio de Oncologia
Malaga, Spain
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Reference Study ID Number: MO29112 ...

Hospital de Navarra; Servicio de Oncologia
Navarra, Spain
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Reference Study ID Number: MO29112 ...

Complejo Hospitalario de Orense; Servicio de Oncologia
Orense, Spain
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Reference Study ID Number: MO29112 ...

Hospital General Universitario de Valencia; Servicio de oncologia
Valencia, Spain
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Reference Study ID Number: MO29112 ...

Hospital Clinico Universitario de Valencia; Servicio de Onco-hematologia
Valencia, Spain
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Reference Study ID Number: MO29112 ...

Hospital Universitario la Fe; Servicio de Oncologia
Valencia, Spain
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Reference Study ID Number: MO29112 ...

Hospital Clinico Universitario Lozano Blesa; Servicio de Oncologia
Zaragoza, Spain
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Reference Study ID Number: MO29112 ...

Hospital Universitario Miguel Servet; Servicio Oncologia
Zaragoza, Spain
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Reference Study ID Number: MO29112 ...

Sk nes University Hospital, Sk nes Department of Onclology
Lund, Sweden
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Reference Study ID Number: MO29112 ...

Karolinska Hospital; Oncology - Radiumhemmet
Stockholm, Sweden
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Reference Study ID Number: MO29112 ...

Acibadem University School of Medicine, Adana Hospital; General Surgery
Adana, Turkey
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Reference Study ID Number: MO29112 ...

Trakya University Medical Faculty Research And Practice Hospital Medical Oncology Department
Edirne, Turkey
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Reference Study ID Number: MO29112 ...

Istanbul Uni Capa Medical Faculty; Inst. of Oncology
Istanbul, Turkey
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Reference Study ID Number: MO29112 ...

Marmara Uni Faculty of Medicine; Medical Oncology
Istanbul, Turkey
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Reference Study ID Number: MO29112 ...

Ege Uni Medical Faculty Hospital; Oncology Dept
Izmir, Turkey
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