Last updated on February 2018

A Study Of PF-05280586 (Rituximab-Pfizer) Or MabThera (Rituximab-EU) For The First-Line Treatment Of Patients With CD20-Positive Low Tumor Burden Follicular Lymphoma (REFLECTIONS B328-06)


Brief description of study

This study will compare the safety and effectiveness of PF-05280586 versus rituximab-EU in patients with CD20-positive, low tumor burden follicular lymphoma. The primary hypothesis to be tested in this study is that the effectiveness of PF-05280586, as measured by the Overall Response Rate, is similar to that of rituximab-EU.

Clinical Study Identifier: NCT02213263

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1184 N. Euclid St.
Anaheim, CA United States

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Pacific Cancer Medical Center, Inc.
Anaheim, CA United States

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East Valley Hematology Oncology Medical Group
Burbank, CA United States

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Apteka Dolnoslaskiego Centrum Transplantacji Komorkowych z Krajowym Bankiem Dawcow Szpiku
Wroclaw, Poland

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Unidade Local de Saude de Matosinhos E.P.E. - Hospital Pedro Hispano S.A.
Matosinhos, Portugal

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Hospital de Braga
Braga, Portugal

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Lisboa, Portugal

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CIMC
Porto, Portugal

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Dr. Campos Costa Clinic
Porto, Portugal

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Centro Hospitalar do Porto-Hospital de Santo Antonio E.P.E.
Porto, Portugal

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Instituto Portugues de Oncologia do Porto Francisco Gentil E.P.E
Porto, Portugal

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Centro Hospitalar de Vila Nova de Gaia/Espinho
Vila Nova de Gaia, Portugal

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Modern Radiology, PSC
Coto Laurel, Puerto Rico

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Caribe MRI and CT
Ponce, Puerto Rico

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Ponce, Puerto Rico

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Institutul Oncologic Prof. Dr. Ion Chiricuta, Sectia Oncologie Medicala
Cluj-Napoca, Romania

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Policlinica de Diagnostic Rapid SA
Brasov, Romania

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Spitalul Clinic Colentina
Bucuresti, Romania

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Hiperdia Ritmului
Bucuresti, Romania

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Affidea Fundeni
Bucuresti, Romania

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Affidea Romania SRL
Bucuresti, Romania

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Spitalul Clinic Coltea, Clinica de Hematologie
Bucuresti, Romania

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Institutul Oncologic Prof. Dr. Ion Chiricuta, Laborator Radiologie si Imagistica Medicala
Cluj-Napoca, Romania

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Cluj-Napoca, Romania

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CT Clinic S.R.L.
Cluj-Napoca, Romania

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Medlife Policlinica De Diagnostic Rapid
Judetul Brasov, Romania

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A.Tsyb Medical Radiological Research Centre -
Obninsk, Russian Federation

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State Healthcare Institution Republican Oncology Dispensary
Saransk, Russian Federation

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"SBHI of NNR ""Nizhniy Novgorod Regional Clinical Hospital n.a. N.A. Semashko"""
Nizhniy Novgorod, Russian Federation

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LLC MC "MRT-Diagnostika"
Nizhniy Novgorod, Russian Federation

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FSBI "Russian Research Centre of Radiology and Surgical Technologies" of MoH of RF
Saint-Petersburg, Russian Federation

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FSBI "Russian Research Centre of Radiology and Surgical Technologies"
Saint-Petersburg, Russian Federation

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FSBI Russian Research Centre of Radiology and Surgical Technologies of MoH of RF
Saint-Petersburg, Russian Federation

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Branch office of LLC 'PET-Technology' at Ufa city
Ufa, Russian Federation

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Private medical institution "Euromedservice"
Pushkin, Russian Federation

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FSBI "Russian Research Centre of Radiology and Surgical Technologies" of MoH of RF
Pesochniy town, Russian Federation

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Federal State Budgetary Institution of Healthcare "Clinical Hospital #101 of Federal
Lermontov, Russian Federation

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SBHI of Stavropol Region "Pyatigorsk Oncology Dispensary"
Pyatigorsk, Russian Federation

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"SBHI ""Chelyabinsk Regional Clinical Oncology Dispensary"""
Chelyabinsk, Russian Federation

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Russian Cancer Research Centre them N.N. Blokhin
Moscow, Russian Federation

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LLC "VitaMed"
Moscow, Russian Federation

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SBHI of Moscow City Clinical Hospital n.a. S.P.Botkin of Healthcare Department of Moscow
Moscow, Russian Federation

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Ramsay Diagnostics
Moscow, Russian Federation

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Dr. Berezin Medical Institute(imaging only)
Saint-Petersburg, Russian Federation

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N.P. Bechtereva Institute of Human Brain of the Russian Academy of Sciences
Saint-Petersburg, Russian Federation

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N.P. Bechtereva Institute of the Human Brain of the Russian Academy of Sciences
Saint-Petersburg, Russian Federation

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FSBI 'Scientific-Research Oncology Institute n.a. N.N.Petrov' of MoH of RF
Saint-Petersburg, Russian Federation

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Non-state healthcare institution "Road Clinical Hospital of Joint Stock Company "Russian Railways"
Saint-Petersurg, Russian Federation

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Yaroslavl State Medical Academy
Yaroslavl, Russian Federation

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"GBUZ of Yaroslavl Region "" Regional Clinical Hospital"""
Yaroslavl, Russian Federation

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NIKSCH & PARTNERS t/a CAPITAL RADIOLOGY
Groenkloof, South Africa

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The Medical Oncology Centre of Rosebank
Johannesburg, South Africa

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Department of Medical Oncology, University of Pretoria, Steve Biko Academic Hospitals Complex
Pretoria, South Africa

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Dr JN De Jong and Partners t/a East Rad
Pretoria, South Africa

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NIKSCH & PARTNERS t/a CAPITAL RADIOLOGY
Pretoria, South Africa

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Albert Alberts Stem Cell Transplant Centre
Pretoria, South Africa

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Drs Sulman & Partners Specialist Radiologists
Rosebank, South Africa

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Drs Bloch & Partners Incorporated
Sandton, South Africa

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Hospital Parc Tauli
Sabadell, Spain

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Onkologikoa
San Sebastian, Spain

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Hospital Universitario Sanitas La Zarzuela
Aravaca, Spain

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Mostoles, Spain

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El Palmar, Spain

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Vigo, Spain

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Complejo Hospitalario Universitario A Coruna
A Coruna, Spain

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Hospital Modelo
A Coruna, Spain

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Barcelona, Spain

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Hospital Quiron de Barcelona, IEC
Barcelona, Spain

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CETIR, Centre Medic
Barcelona, Spain

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Radiodiagnostic CETIR - Clinica del Pilar
Barcelona, Spain

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Hospital Universitario Puerta del Mar
Cadiz, Spain

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Hospital Universitario Fundacion Jimenez Diaz
Madrid, Spain

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Hospital Universitario Sanitas La Moraleja
Madrid, Spain

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Centro CIMES
Malaga, Spain

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Hospital universitario Virgen de la Victoria
Malaga, Spain

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Centro Mario Gallegos
Malaga, Spain

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Complejo Hospitalario de Ourense. Hematolog a
Ourense, Spain

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Hospital Universitario Virgen del Rocio
Sevilla, Spain

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H. Quiron Zaragoza
Zaragoza, Spain

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Hospital de Dia Quiron Zaragoza
Zaragoza, Spain

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Inselspital Bern
Bern, Switzerland

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Apotheke, Spital STS AG
Thun, Switzerland

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Onkologiezentrum Thun-Berner Oberland Spital Sts Ag
Thun, Switzerland

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UniversitaetsSpital Zuerich
Zuerich, Switzerland

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Cardiology Unit,Department of Medicine, Faculty of Medicine, Ramathibodi Hospital,
Bangkok, Thailand

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National Cancer Institute
Bangkok, Thailand

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Hacettepe Universitesi Tip Fakultesi Onkoloji Hastanesi
Ankara, Turkey

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Dr. Abdurrahman Yurtaslan Ankara Onkoloji Eg. ve Aras.
Ankara, Turkey

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Ultramar Tibbi Gorunteleme Merkezi
Ankara, Turkey

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Ultramar Tibbi Goruntuleme Merkezi
Ankara, Turkey

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Integra Gurses Teshis Tedavi ve Saglik Hizmetleri A.S.
Ankara, Turkey

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Adnan Menderes University Medical Faculty
Aydin, Turkey

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Gaziantep Universitesi Tip Fakultesi Onkoloji Hastanesi
Gaziantep, Turkey

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Gaziantep Universitesi Sahinbey Arastirma ve Uygulama Hastanesi
Gaziantep, Turkey

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Bezmialem Vakif Universitesi Tip Fakultesi Hastanesi
Istanbul, Turkey

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Ege Universitesi Tip Fakultesi Ic Hastaliklari Anabilim Dali
Izmir, Turkey

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EGE-RAD Bilgisayarli Tomografi Ozel Saglik Hizmetleri ve Malzemeleri Tic.Ltd.Sti.
Izmir, Turkey

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Erciyes Universitesi Tip Fakultesi
Kayseri, Turkey

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Inonu Universitesi Tip Fakultesi Turgut Ozal Tip Merkezi
Malatya, Turkey

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Celal Bayar University Medical Faculty
Manisa, Turkey

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Ondokuz Mayis Universitesi Tip Fakultesi
Samsun, Turkey

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"Mediks-rey International Group" LLC
Obukhiv district, Ukraine

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MI 'City Dnipropetrovsk Multi-field Clin. Hospital #4 of DRC'
Dnipropetrovsk, Ukraine

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National Cancer Institute
Kyiv, Ukraine

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"Central City Clinical Hospital, City Oncology Center, SHEI ""Uzhhorod National University"", Chair
Uzhhorod, Ukraine

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Vinnytsia Regional Oncology Clinical Dispensary, Chemotherapy Department
Vinnytsia, Ukraine

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Municipal Establishment 'Zaporizhzhia Regional Clinical Oncology Dispensary' of the ZRC
Zaporizhzhia, Ukraine

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LLC "Diaservis"
Zaporizhzhia, Ukraine

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Cobalt Diagnostic Imaging
Cheltenham, United Kingdom

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Royal United Hospital
Bath, United Kingdom

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Southend University Hospital NHS Foundation Trust
Essex, United Kingdom

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Barts Health NHS Trust
London, United Kingdom

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Positron Emission Tomography (PET) Centre
Newcastle upon Tyne, United Kingdom

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City Hospitals Sunderland NHS Foundation Trust-Sunderland Royal Hospital
Sunderland, United Kingdom

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Diagnostic Imaging
Sunderland, United Kingdom

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Sunderland Royal Hospital
Sunderland, United Kingdom

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Torrance Health Association DBA, Torrance Memorial Physician, Network/Cancer Care Associates
Redondo Beach, CA United States

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Rocky Mountain Cancer Center Pueblo
Pueblo, CO United States

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Maryland Oncology Hematology P. A.
Wheaton, MD United States

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Brody School of Medicine at East Carolina University
Greenville, NC United States

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Texas Oncology-Tyler
Tyler, TX United States

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SI Republican Research and Practice Centre of oncology and medical radiology n.a N.N Alexandrov
Republic Of Belarus, Belarus

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Nuclear Medicine Department
Brussels, Belgium

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Hospital das Clinicas da Universidade Federal de Goias \ Centro de Pesquisa Clinica -
Goiania, Brazil

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Hospital das Clinicas da Universidade Federal de Goias \ Centro de Pesquisa Clinica
Goiania, Brazil

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Hospital de Clinicas de Porto Alegre - Centro de Pesquisa Clinica
Porto Alegre, Brazil

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Hospital de Clinicas de Porto Alegre
Porto Alegre, Brazil

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Centro De Pesquisas Clinicas
Jau, Brazil

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CEMEDI
Campinas, Brazil

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Instituto Radium
Campinas, Brazil

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IEP Sao Lucas - Instituto de Ensino e Pesquisa Sao Lucas / HEMOMED -
Sao Paulo, Brazil

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IEP S o Lucas (Pharmacy)
São Paulo, Brazil

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Casa de Saude Santa Marcelina
Sao Paulo, Brazil

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Charite - Universitatsmedizin Berlin - Campus Benjamin Franklin
Berlin, Germany

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Charite - Universitatsmedizin Berlin
Berlin, Germany

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Universitatsklinikum Essen (AOR)
Essen, Germany

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Universitatsklinikum Essen
Essen, Germany

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Gen. Hosp. of Athens "Evangelismos - Eye Hosp.- Polikliniki"
Athens, Greece

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Gen. Hosp. of Athens "Evangelismos-Eye Hosp.-Polikliniki"
Athens, Greece

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Bioiatriki S.A.
Athens, Greece

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Magnitiki Patron
Patras, Greece

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"Dipartimento di Biotecnologie Cellulari ed Ematologia, Universita ""Sapienza""
Rome, Italy

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Padiglione 1, Torre delle medicine, 6 piano
Parma, Italy

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East Nagoya Imaging Diagnosis Center
Nagoya, Japan

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Kobe City Medical Center General Hospital
Kobe-City, Japan

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Middle East Institute Of Health
El Metn, Lebanon

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Ain Wazein Hospital
Mount Lebanon, Lebanon

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Pet Scan Peru
Lima, Peru

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Resocentro
Lima, Peru

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Ad-Vance Medical Research, LLC
Ponce, Puerto Rico

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State Budgetary Healthcare Institution "Republican Clinical Oncology Dispensary of the Ministry
Ufa, Russian Federation

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FSBI "Russian Research Centre of Radiology and Surgical Technologies" of MoH of RF
Pesochniy Town, Russian Federation

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"State Budgetary Institution of Healthcare ""Leningrad Regional Clinical Hospital"""
Saint Petersburg, Russian Federation

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Universitatsspital Basel
Basel, Switzerland

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Kantonsapotheke Zuerich
Zuerich, Switzerland

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UniversitaetsSpital Zuerich (University Hospital Zurich)
Zuerich, Switzerland

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Department of Radiology, Ramathibodi Hospital
Bangkok, Thailand

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Erciyes Universitesi Tip Fakultesi Nukleer Tip Laboratuvari
Kayseri, Turkey

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Erciyes Universitesi Tip Fakultesi Radyoloji Laboratuvari
Kayseri, Turkey

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"Mediks-rey International Group" LLC
Obukhiv District, Ukraine

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"MedX-rey International Group" LLC
Obukhiv District, Ukraine

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"MedX-Ray International Group" LLC
Obukhiv, Ukraine

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"Municipal Institution ""Chernivtsi Regional Clinical Oncology Center"",
Chernivtsi, Ukraine

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Municipal Non-Profit Enterprise "Regional Oncology Centre"
Kharkiv, Ukraine