Last updated on March 2017

A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) Inhibitors (Study #2)


Brief description of study

This phase III, double blind, placebo and active comparator controlled, multicenter study will investigate the efficacy and safety of etrolizumab in induction of remission in participants with moderately to severely active UC who are naïve to TNF inhibitors and refractory to or intolerant of prior immunosuppressant and/or corticosteroid treatment.

Clinical Study Identifier: NCT02171429

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Community Clinical Trials
Orange, CA United States
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Digestive Care Associates, A Medical Corporation
San Carlos, CA United States
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Medical Associates Research Group, Inc.
San Diego, CA United States
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Rocky Mountain Gastroenterology Associates
Denver, CO United States
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Medical Research Center of Connecticut, LLC
Hamden, CT United States
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Advanced Research Institute
New Port Richey, FL United States
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Internal Medicine Specialists
Orlando, FL United States
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Atlanta Center for Gastroenterology, PC
Decatur, GA United States
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Gastrointestinal Specialists of Georgia, PC
Marietta, GA United States
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Cotton-O'Neil Clinical Research Center, Digestive Health
Topeka, KS United States
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Meritus Center for Clinical Research
Hagerstown, MD United States
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Massachusetts General Hospital; Crohn's & Colitis Center
Boston, MA United States
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University of Michigan Health System
Ann Arbor, MI United States
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Kansas City Research Institute, LLC
Kansas City, MO United States
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Atlantic Gastroenterology Associates
Egg Harbor Township, NJ United States
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MS Comprehensive Care Center
Teaneck, NJ United States
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North Shore University Hospital
Manhasset, NY United States
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Concorde Medical Group
New York, NY United States
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Premier Medical Group of the Hudson Valley PC
Poughkeepsie, NY United States
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University of North Carolina at Chapel Hill - Department of Family Medicine; CB# 7295
Chapel Hill, NC United States
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Atlantic Medical Group
Kinston, NC United States
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Great Lakes Gastroenterology Research, LLC
Mentor, OH United States
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Clinical Trials of South Carolina
North Charleston, SC United States
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Gastro One
Germantown, TN United States
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Quality Medical Research
Nashville, TN United States
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Pioneer Research Solutions
Houston, TX United States
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National Clinical Research Inc.-Richmond
Richmond, VA United States
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Virginia Commonwealth Uni Health Center
Richmond, VA United States
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Digestive Disease Institute; Virginia Mason Medical Center
Seattle, WA United States
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Dean and St. Mary's Outpatient Center; Medical Research
Madison, WI United States
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Centro Medico Viamonte SRL
Ciudad Autonoma de Buenos Aires, Argentina
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Consultorios Independencia
Cordoba, Argentina
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Hospital Privado Centro Medico de Cordoba
Córdoba, Argentina
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Centro de Investigaciones Medicas Mar Del Plata
Mar del Plata, Argentina
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Hospital Privado de Comunidad; Cardiology
Mar Del Plata, Argentina
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Hospital Luis Lagomaggiore
Mendoza, Argentina
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Instituto Medico CER
Quilmes, Argentina
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Sanatorio 9 de Julio SA
Tucuman, Argentina
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Concord Repatriation General Hospital
Concord, Australia
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Royal Adelaide Hospital
Adelaide, Australia
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Flinders Medical Centre
Bedford Park, Australia
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St Vincent's Hospital Melbourne
Fitzroy, Australia
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Footscray Hospital; Gastroenterology
Footscray, Australia
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Hospital Universit rio Professor Edgard Santos - Universidade Federal da Bahia
Salvador, Brazil
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CMiP - Centro Mineiro de Pesquisa
Juiz de Fora, Brazil
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Funda o Imepen - Instituto Mineiro de Estudos e Pesquisas em Nefrologia
Juiz de Fora, Brazil
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Hospital Ernesto Dornelles
Porto Alegre, Brazil
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Hospital S o Lucas da PUCRS
Porto Alegre, Brazil
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Medical Centre "Asklepii", OOD
Dupnitsa, Bulgaria
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DCC Sv. Pantaleymon OOD
Pleven, Bulgaria
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UMHAT 'Dr. Georgi Stranski', EAD
Pleven, Bulgaria
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MHAT "Eurohospital" - Plovdiv, OOD
Plovdiv, Bulgaria
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MHAT "Lyulin", EAD
Sofia, Bulgaria
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"City Clinic UMHAC" EOOD
Sofia, Bulgaria
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MHAT Tokuda Hospital Sofia, AD
Sofia, Bulgaria
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MHAT "Evropa", OOD
Sofia, Bulgaria
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Medical Center "Nov Rehabilitatsionen Tsentar", EOOD
Stara Zagora, Bulgaria
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MHAT 'Sv. Marina', EAD
Varna, Bulgaria
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Clinica Universitaria Colombia
Bogota, Colombia
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RTS - Fundaci n Valle de Lili
Cali, Colombia
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Hospital Pablo Tobon Uribe
Medellin-Antioquia, Colombia
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Instituto de Coloproctologia ICO S.A.S.
Medellin, Colombia
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Clinical Hospital Centre Osijek
Osijek, Croatia
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General Hospital Pula
Pula, Croatia
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General Hospital Varazdin
Varazdin, Croatia
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Clinical Hospital Centre Zagreb
Zagreb, Croatia
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Clinical Hospital Dubrava
Zagreb, Croatia
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Clinical Hospital Sveti Duh
Zagreb, Croatia
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University General Hospital of Alexandroupolis
Alexandroupolis, Greece
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General Hospital of Athens "Evangelismos"
Athens, Greece
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District General Hospital of Athens Laiko; 1st Internal Medicine Clinic
Athens, Greece
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General Hospital of Nea Ionia "Kostantopoulio"
Athens, Greece
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University General Hospital of Heraklion
Herakleion, Greece
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Interbalkan Hospital
Pilaia Thessalonikis, Greece
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Anticancer Hospital of Thessaliniki " Theagenio"
Thessaloniki, Greece
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General Hospital of Thessaloniki G. Papanikolaou
Thessaloniki, Greece
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