Last updated on March 2014

Effect of DBS on Quality of Life in Dyskinetic Cerebral Palsy


Brief description of study

There are limited therapeutical options for patients with secondary dystonia due to cerebral palsy. Pharmacotherapy is often without effect, or side effects are severe. Meanwhile deep brain stimulation (DBS) has proven to be a safe and effective therapy for patients with parkinson´s disease or primary / idiopathic dystonia. Experiences with DBS in patients with dyskinetic cerebral palsy are limited with heterogeneous data. With STIM-CP we investigate the effect of DBS on quality of life in young patients with a dyskinetic movement disorder (dyskinetic cerebral palsy) due to perinatal hypoxic brain injury. Additionally, the effect of DBS on motor development, speech, memory, attention, cognition and pain perception will be assessed. In total, 20 patients aged 7-18 years diagnosed with dyskinetic cerebral palsy, who will receive DBS, should be included. 11 German DBS-centres will participate in the trial. We assume that DBS reduces the severity of dystonia and improves the quality of life in these patients.

Clinical Study Identifier: NCT02097693

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Anne Koy, MD

University Hospital Cologne
Cologne, Germany
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