Last updated on April 2017

Prevention of Macular Edema In Patients With Diabetic Retinopathy Undergoing Cataract Surgery


Brief description of study

To determine the safety and efficacy of intravitreal Aflibercept (Eylea) injection in patients with diabetic retinopathy in the prevention of macular edema following cataract surgery.

Detailed Study Description

Diabetic retinopathy patients who are at risk of developing macular edema (defined as ≥ 30 % increase from pre-operative baseline in central subfield macular thickness) within 90 days following cataract surgery. Diabetic patients are defined as those who have either Type 1 or Type 2 diabetes. The patients must have either mild, moderate, or severe non proliferative retinopathy or treated proliferative retinopathy. Patients must be 18 years of age and older, of any race and either sex, requiring cataract extraction with planned implantation of a posterior chamber intraocular lens into the lens capsule.

Clinical Study Identifier: NCT01988246

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Rishi Singh, M.D.

Cole Eye Institute, Cleveland Clinic
Cleveland, OH United States
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