Last updated on October 2016

Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE)


Brief description of study

The purpose of this study is to determine whether ornithine phenylacetate can speed recovery from an acute hepatic encephalopathy episode requiring hospitalization in cirrhotic patients.

Detailed Study Description

This is a multicenter, randomized, double-blind, placebo-controlled study of ornithine phenylacetate (OCR-002) administered intravenously to hospitalized patients with cirrhosis, hyperammonemia, and an acute episode of hepatic encephalopathy administered on top of standard of care treatment.

Clinical Study Identifier: NCT01966419

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Jennifer Atwell

Phoenix, AZ United States
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Jennifer Atwell

Little Rock, AR United States
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Jennifer Atwell

Coronado, CA United States
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Los Angeles, CA United States
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San Francisco, CA United States
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New Haven, CT United States
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Miami, FL United States
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Atlanta, GA United States
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Chicago, IL United States
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Glenview, IL United States
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Iowa City, IA United States
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New Orleans, LA United States
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Baltimore, MD United States
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Bethesda, MD United States
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Boston, MA United States
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Minneapolis, MN United States
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Jackson, MS United States
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Columbia, MO United States
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Newark, NJ United States
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Buffalo, NY United States
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New York, NY United States
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Chapel Hill, NC United States
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Columbus, OH United States
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Philadelphia, PA United States
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Pittsburgh, PA United States
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Charleston, SC United States
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Nashville, TN United States
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Dallas, TX United States
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Houston, TX United States
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Richmond, VA United States
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Seattle, WA United States
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Milwaukee, WI United States
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Kingswood, Australia
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Adelaide, Australia
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Bedford Park, Australia
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Melbourne, Australia
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Fitzroy Victoria, Australia
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Parkville, Australia
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Bruxelles, Belgium
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Praha, Czech Republic
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Copenhagen, Denmark
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Hvidovre, Denmark
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Villejuif, France
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Heidelberg, Germany
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Debrecen, Hungary
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Kaposvar, Hungary
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Jerusalem, Israel
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Petah-Tikva, Israel
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Ramat-Gan, Israel
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San Giovanni Rotondo, Italy
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Leiden, Netherlands
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Maastricht, Netherlands
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Auckland, New Zealand
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Moscow, Russian Federation
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Samara, Russian Federation
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Jennifer Atwell

Pontevedra, Spain
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