Last updated on February 2018

Nintedanib (BIBF 1120) in Mesothelioma


Brief description of study

This is a phase II/III confirmatory study designed to evaluate the safety and efficacy of nintedanib (BIBF 1120) in combination + (pemetrexed / cisplatin) followed by nintedanib (BIBF 1120) versus placebo + pemetrexed / cisplatin followed by placebo for the treatment of patients with unresectable malignant pleural mesothelioma.

Clinical Study Identifier: NCT01907100

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Boehringer Ingelheim Call Center

University of Alabama at Birmingham
Birmingham, AL United States

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Rocky Mountain Cancer Centers
Colorado Springs, CO United States

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Comprehensive Cancer Centers of Nevada- Peak Office
Henderson, NV United States

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University of Pittsburgh Medical Center
Pittsburgh, PA United States

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Greenville Health System
Greenville, SC United States

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The University of Texas MD Anderson Cancer Center
Houston, TX United States

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Texas Oncology - McAllen
McAllen, TX United States

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Texas Oncology-San Antonio Northeast
San Antonio, TX United States

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Cancer Care Northwest Centers, PS
Spokane Valley, WA United States

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Cl nica Universitaria Reina Fabiola
Ciudad de Cordoba, Argentina

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Northern Cancer Institute
St Leonards, Australia

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Calvary Mater Newcastle Hospital
Waratah, Australia

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The Prince Charles Hospital
Chermside, Australia

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Mater Cancer Care Centre
South Brisbane, Australia

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Box Hill Hospital
Box Hill, Australia

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Peninsula Haematology & Oncology
Frankston, Australia

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Austin Health
Heidelberg, Australia

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Border Onclogy Research
Wodonga, Australia

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Sir Charles Gairdner Hospital
Nedlands, Australia

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Perth Oncology
Perth, Australia

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LKH Leoben
Leoben, Austria

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Klinikum Wels - Grieskirchen GmbH
Wels, Austria

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Brussels - UNIV St-Luc
Bruxelles, Belgium

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Edegem - UNIV UZ Antwerpen
Edegem, Belgium

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UNIV UZ Gent
Gent, Belgium

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UZ Leuven
Leuven, Belgium

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QEII Health Sciences Centre (Dalhousie University)
Halifax, NS Canada

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IUCPQ (Laval University)
Quebec, QC Canada

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Centro Internacional de Estudios Cl nicos - CIEC
Recoleta, Chile

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Orlandi Oncologia
Vitacura, Chile

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University Clinic for Pulmonary Diseases
Zagreb, Croatia

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University Hospital Brno
Brno, Czechia

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University Hospital Olomouc
Olomouc, Czechia

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Clinical Research Center Alexandria
Alexandria, Egypt

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Medical Research Institute
Alexandria, Egypt

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National Cancer Institute, Cairo University
Cairo, Egypt

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Nasser Institute
Cairo, Egypt

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HOP Morvan
Brest, France

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HOP C te de Nacre
Caen, France

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HOP Calmette
Lille, France

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HOP Nord
Marseille, France

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HOP Larrey
Toulouse, France

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INS Gustave Roussy
Villejuif, France

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Vivantes Netzwerk f r Gesundheit GmbH
Berlin, Germany

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HELIOS Klinikum Emil von Behring GmbH
Berlin, Germany

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Klinik Schillerh he, Gerlingen
Gerlingen, Germany

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Thoraxklinik-Heidelberg gGmbH am Universit tsklinikum Heidelberg
Heidelberg, Germany

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Universit tsklinikum des Saarlandes
Homburg/Saar, Germany

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Soroka Univ. Medical Center
Beer Sheva, Israel

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Rambam Medical Center
Haifa, Israel

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Meir Medical Center
Kfar-Saba, Israel

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Rabin Medical Center Beilinson
Petach Tikva, Israel

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Sourasky Medical Center
Tel-Aviv, Israel

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Azienda Ospedaliera Santi Antonio e Biagio e Cesare Arrigo
Alessandria, Italy

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Humanitas Gavazzeni
Bergamo, Italy

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Istituto Nazionale per la Ricerca sul Cancro
Genova, Italy

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A.O. San Gerardo di Monza
Monza, Italy

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Azienda Sanitaria Ospedale S. Luigi Gonzaga
Orbassano (TO), Italy

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A.O. S.Maria degli Angeli
Pordenone, Italy

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A.O.U. Senese Policlinico Santa Maria alle Scotte
Siena, Italy

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Ospedale S. Giuseppe Moscati
Statte (TA), Italy

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University Hospital of Occupational and Environmental Health
Fukuoka, Kitakyushu, Japan

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Hyogo Prefectural Amagasaki General Medical Center
Hyogo, Amagasaki, Japan

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Hyogo College of Medicine Hospital
Hyogo, Nishinomiya, Japan

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Yokosuka Kyosai Hospital
Kanagawa , Yokosuka, Japan

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Japan Labour Health and Safety Organization Okayama Rosai Hospital
Okayama, Okayama, Japan

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Kindai University Hospital
Osaka, OsakaSayama, Japan

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Otemae Hospital
Osaka, Osaka, Japan

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Juntendo University Hospital
Tokyo, Bunkyo-ku, Japan

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Centro Oncologico de Chihuahua
Chihuahua, Mexico

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Instituto Nacional de Cancerologia
Mexico, Mexico

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Centro Oncologico Estatal ISSEMYM
Toluca, Mexico

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Medisch Spectrum Twente
Enschede, Netherlands

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Zuyderland Medisch Centrum
Heerlen, Netherlands

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Erasmus Medisch Centrum
Rotterdam, Netherlands

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St. Olavs Hospital, Universitetssykehuset i Trondheim
Trondheim, Norway

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University Clinical Center, Gdansk
Gdansk, Poland

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Clin. Hosp. of Univ. of Med. Sciences
Poznan, Poland

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Wielkopolski Center Pulmonology+Tuberculosis P-III, Poznan
Poznan, Poland

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Oncol Centre M Sklodowska-Curie, Dept of Lung & Chest Cancer
Warsaw, Poland

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Centro Hospitalar Lisboa Norte Hospital Pulido Valente
Lisboa, Portugal

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Hospital CUF Porto
Porto, Portugal

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IPO Porto Francisco Gentil, EPE
Porto, Portugal

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CHTAD, EPE - Hospital S o Pedro de Vila Real
Vila Real, Portugal

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FGBUZ "Chelyabinsk Reg. Oncology Dispensary";Chemotherpy Dep
Chelyabinsk, Russian Federation

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Republic Clinical Oncology Dispensary, Dept. Chemotherapy
Kazan, Russian Federation

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First Pavlov State Medical University Saint Petersburg
Saint-Petersburg, Russian Federation

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Republican Clinical Oncology Center Ufa
Ufa, Russian Federation

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Wilgers Oncology Centre
Pretoria, South Africa

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Merc Oncology
Pretoria, South Africa

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Hospital Universitario de Cruces
Barakaldo (Vizcaya), Spain

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Hospital Vall d'Hebron
Barcelona, Spain

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Hospital Cl nic de Barcelona
Barcelona, Spain

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Hospital Universitario Donostia
Donostia (Gipuzkoa), Spain

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Hospital Duran i Reynals
L'Hospitalet de Llobregat, Spain

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Hospital Ram n y Cajal
Madrid, Spain

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CS Parc Taul
Sabadell (Barcelona), Spain

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Hospital Virgen del Roc o
Sevilla, Spain

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Hospital Cl nico de Valencia
Valencia, Spain

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Sk nes universitetssjukhus
Lund, Sweden

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Karolinska Univ. sjukhuset
Stockholm, Sweden

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Akademiska sjukhuset
Uppsala, Sweden

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Eskisehir Osmangazi ni. Sag. Uygulama ve Arastirma Has.
Eskisehir, Turkey

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Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi
Istanbul, Turkey

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Dr.Suat Seren EAH
Izmir, Turkey

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Leicester Royal Infirmary
Leicester, United Kingdom

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University of California San Francisco
San Francisco, CA United States

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Sanatorio G emes
Ciudad Autónoma de Bs As, Argentina

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Instituto Medico Especializado Alexander Fleming
Ciudad Autónoma de Bs As, Argentina

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Univ.-Klinik f. Innere Medizin I, Onkologie, Wien
Wien, Austria

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AZ Sint-Maarten
Mechelen, Belgium

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Health Sciences North
Sudbury, ON Canada

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Princess Margaret Cancer Centre
Toronto, ON Canada

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Clinical Hospital Osijek
Osijek, Croatia

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Rigshospitalet, K benhavn, Onkologisk afd
Købenahvn Ø, Denmark

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CLI Bordeaux Nord Aquitaine
Bordeaux, France

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HOP Dupuytren
Limoges, France

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HOP Lyon Sud
Pierre-Bénite, France

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HOP HIA Saint-Anne
Toulon, France

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Pneumologisches Forschungsinstitut an der LungenClinic Grosshansdorf GmbH
Großhansdorf, Germany

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Klinik, L wenstein
Löwenstein, Germany

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Oslo Universitetssykehus HF, Radiumhospitalet
Oslo, Norway

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FSBSI "N.N Blokhin Medical Research Center of Oncology"
Moscow, Russian Federation

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FSBI "N.N. Petrov National Medical Research Center of Oncology" of MoH of RF
Saint-Petersburg, Russian Federation

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Hospital Virgen de la Victoria
Malaga, Spain

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Sahlgrenska US, G teborg
Göteborg, Sweden

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Universitetssjukhuset, Link ping
Linköping, Sweden

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Western General Hospital
Edinburgh, United Kingdom

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Beatson West of Scotland Cancer Centre
Glasgow, United Kingdom

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Guy's Hospital
London, United Kingdom

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The Royal Marsden Hospital
London, United Kingdom

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The Royal Marsden Hospital
Sutton, United Kingdom

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Wythenshawe Hospital
Wythenshawe, United Kingdom