Last updated on April 2009

Non-Invasive Determination of Fetal Chromosome Abnormalities

Brief description of study

The overall significance of this study is to develop a laboratory developed test (LDT) to use a new marker in the maternal blood to better identify pregnancies that have a child with a chromosome abnormality such as Down syndrome (trisomy 21), Edward's syndrome (trisomy 18), Patau syndrome (trisomy 13), Klinefelter syndrome, (47, XXY), and other chromosome abnormalities. Accomplishing that task would reduce the need for invasive amniocentesis and CVS procedures.

Clinical Study Identifier: NCT00891852

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Elizabeth Kramer, GC

Maryland Perinatal Associates
Rockville, MD United States
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Diane London, Perinatal Nurse

Atlantic Maternal Fetal Medicine
Moristown, NJ United States
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Martin Chavez, MD

Winthrop University Hospital
Mineola, NY United States
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Jonathan D Herman, MD

Elite Women's Health
New Hyde Park, NY United States
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Erica Speigel, GC

Columbia University, NewYork-Presbyterian Hospital
New York, NY United States
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Daniel Saltzman, MD

New York Perinatal Associates
New York, NY United States
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Stephen A Brown, MD

Burlington, VT United States
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