Last updated on April 2016

Prospective Study of Scoliosis in Children With Cerebral Palsy


Brief description of study

The purpose of this study is to determine the radiographic and clinical outcomes of Scoliosis surgical treatment in patients with Cerebral Palsy.

Detailed Study Description

Bracing severe neuromuscular scoliotic curves rarely serves as definitive treatment, thus most progressive curves require surgical intervention in order to sustain or improve sitting (or ambulatory) abilities. Surgery is a demanding intervention for these patients, with variable functional gains. Controversy persists regarding indications for surgery, timing, and technique. Concerns about complications are paramount. Previous neuromuscular studies have been confined to a small number of surgeons with a narrow range of surgical instrumentation, technique, and correction. Very little evidence exists regarding the impact spinal surgery on the quality of life in children with scoliosis related to cerebral palsy. The instruments to measure quality of life are not specific to children with scoliosis related to cerebral palsy. There have been no comprehensive prospective studies published. This study would be the first large-scale prospective, multi-center series of spinal fusion outcomes in patients with Cerebral Palsy.

Clinical Study Identifier: NCT00680264

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Peter Newton, MD

Rady Children's Hospital
San Diego, CA United States
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Suken Shah, MD

A.I. Dupont Hospital for Children
Wilmington, DE United States
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Harry Shufflebarger, MD

Miami Children's Hospital
Miami, FL United States
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Paul Sponseller, MD

Johns Hopkins Medical Institute
Baltimore, MD United States
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Jack Flynn, MD

Children's Hospital of Philadelphia
Philadelphia, PA United States
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Patrick Cahill, MD

Shriners Hospital for Children
Philadelphia, PA United States
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Dan Sucato, MD

Texas Scottish Rite Hospital
Dallas, TX United States
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Mark Abel, MD

Kluge Children's Rehab. Ctr.
Charlottesville, VA United States
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Jean Ouellet, MD, FRCSC

Children's Hospital
Montreal, Canada
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Hubert Labelle, MD

CHU Saint-Justine Hospital
Montreal, Canada
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Unni G Narayanan, MBBS

Hospital for Sick Children
Toronto, Canada
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Chris Reilly, MD

British Columbia Children's Hospital
Vancouver, Canada
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