Last updated on March 2018

Pathophysiology of Orthostatic Intolerance


Brief description of study

The purpose of this study is to describe the mechanism of orthostatic intolerance, relying on cardiovascular physiological studies. The syndrome is of undetermined etiology, but the syndrome causes impairment of a number of young adults, females more than males, with symptoms of tachycardia, fatigue, lightheadedness, palpitations, blurred vision, chest discomfort, difficulty concentrating, and dizziness with the upright posture. It is believed that many different pathophysiological processes can give rise to this disorder.

Clinical Study Identifier: NCT00608725

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David Robertson, M.D.

Vanderbilt University
Nashville, TN United States
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