Last updated on August 2007

Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer


Brief description of study

Correct identification of Lynch syndrome at the time of colorectal cancer presentation is important. We aim to find best ways to screen patients with colorectal cancer in Korea.

Detailed Study Description

Patients with newly diagnoised colorectal cancer will be eligible. They will undergo detailed history taking including family history, and molecular stuidies including microsatellite instability test and immunohistochemistry for DNA mismatch repair protein with pre-selection. Any abnormal finding in molecular stuides will be offered genetic testing (after testing methylation status for patients with abnormalities in MLH1).

Clinical Study Identifier: NCT00516230

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Tae Kyun Kim

Samsung Medical Center
Seoul, Korea, Republic of
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