Last updated on March 2007

Pharmacokinetic and Pharmacodynamic Effects of MTR107 in End-Stage Renal Disease (ESRD) Patients


Brief description of study

MTR107 effect on blood pressure throught the dialysis procedure and its ability to prevent Intra dialytic Hypotension

Detailed Study Description

The present clinical trial aims to investigate and provide a more precise characterization of the pharmacokinetic and pharmacodynamic profile of MTR107 in a population of ESRD patients predisposed to developing intradialytic hypotension. The study is also designed as a dose esclating study aiming to assess MTR107 safety.

Clinical Study Identifier: NCT00448071

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Zeev Katzir, MD

Wolfson Medical Center
Holon, Israel
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Shay Efrati, MD

Asaf Harofeh Medical Center
Rishon Le Zion, Israel
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