Last updated on July 2010

Efficacy and Safety of Psychopharmacotherapy in Patients With Schizophrenia or Bipolar Disorders


Brief description of study

The purpose of this study is to investigate the efficacy and safety of long-term psychopharmacotherapy in schizophrenia or bipolar disorder in terms of psychopathology and side effects.

Detailed Study Description

Schizophrenia and bipolar disorder are renowned for chronic and deteriorating course. Although atypical antipsychotics and mood stabilizers are widely used as treatment of choice for these illness based on acute efficacy and safety, long-term efficacy and safety of these agents are still open to debate. Prospective follow-up study in naturalistic condition may be a useful way of elucidating cons and pros of long-term psychopharmacotherapy.In this study, efficacy and various side effects of drugs will be measured, and the possibility of neurophysiological markers will be tested by serial measurements of electroencephalographic changes.

Clinical Study Identifier: NCT00330226

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Jae Seung Chang, MD

Seoul National University Hospital
Seoul, Korea, Republic of
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