Last updated on September 2006

Feasibility Study of Phototherapy System to Treat H Pylori


Brief description of study

This purpose of this study is to determine whether phototherapy can be used to safely and effectively treat H pylori.

Detailed Study Description

H pylori causes almost all peptic ulcers and many gastric cancers and is widely prevalent worldwide. Treatment by multiple antibiotics and proton pump inhibitors is effective but are compromised today by significant non compliance due to side effects and duration of required treatment. Also, the increase in antibiotic resistance coupled with the decreased availability of new antibiotics project a significant population of patients who will not be treatable with antibiotics. A special, visible-light based phototherapy system has been demonstrated to significantly decrease the viability of H pylori in vitro and in a brief clinical experiment. This study will evaluate the safety and short term efficacy in up to 60 patients of the phototherapy system to treat H pylori.

Clinical Study Identifier: NCT00306280

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Anthony Lembo

Beth Israel Deaconness Medical Center
Boston, MA United States
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David Cave

UMass Memorial Medical Center
Worcester, MA United States
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Robert Ganz

Abbott Northwestern Hospital
Minneapolis, MN United States
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