Last updated on November 2017

B51 A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chest wall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy


Brief description of study

B51 A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chest wall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy

Detailed Study Description

The purpose of this clinical trial is to study patients with positive nodes before chemotherapy who become negative after chemotherapy to see1) if, after lumpectomy (surgery to remove cancer), radiation to the breast and lymph nodes will be better than radiation only to the breast at keeping cancer from returning, and 2) if, after mastectomy (surgery to remove part or all of one or both breasts), radiation to the area where the breast used to be and to the lymph nodes is better than no radiation at keeping cancer from returning.

Clinical Study Identifier: TX3025

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Drashti Shah

AMITA Health
Arlington Heights, IL USA
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