Last updated on April 2017

Tisotumab Vedotin (HuMax -TF-ADC) Safety Study in Patients With Solid Tumors


Brief description of study

The purpose of the trial is to establish the tolerability of tisotumab vedotin (HuMax-TF-ADC) in a mixed population of patients with specified solid tumors

Detailed Study Description

The study is conducted in two parts. The dose escalation portion of the trial subjects are enrolled into cohorts at increasing dose levels of tisotumab vedotin (HuMax-TF-ADC) in 28 day treatment cycles. In the Cohort Expansion part of the trial, will further explore the recommended phase 2 dose of tisotumab vedotin (HuMax-TF-ADC) as determined in Part 1

Clinical Study Identifier: NCT02552121

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David S Hong, MD

MD Anderson Cancer Center
Houston, TX United States
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Joseph Kerger, MD

Institut Jules Bordet
Bruxelles, Belgium
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Nicole Concin, MD

Universitaire Ziekenhuizen Leuven
Leuven, Belgium
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Jean-Luc Canon, MD

Grand H pital de Charleroi
Charleroi, Belgium
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Christine Gennigens, MD

CHU de Li ge
Liege, Belgium
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Lionel D'Hondt, MD

CHU UCL Namur - site Godinne
Yvoir, Belgium
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Jean-François Baurain, MD

Cliniques Universitaires Saint-Luc
Brussels, Belgium
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Peter Vuylsteke, MD

CHU UCL Namur - Sainte Elisabeth
Namur, Belgium
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Ulrik Lassen, MD

Rigshospitalet, Copenhagen University Hospital
Copenhagen, Denmark
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Tamás Pintér, MD

Petz Alad r Megyei Oktat K rh z
Gyor, Hungary
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Róbert Póka, MD

Debreceni Egyetem Klinikai K zpont
Debrecen, Hungary
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Magdolna Dank, MD

Semmelweis Egyetem Onkol giai K zpont
Budapest, Hungary
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Rebecca Kristeleit, MD

University College London Hospitals NHS Foundation Trust
London, United Kingdom
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Hendrik-Tobias Arkenau, MD

Sarah Cannon Cancer Center
London, United Kingdom
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Emma Dean, MD

The Christie NHS Foundation Trust
Manchester, United Kingdom
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Johann de Bono, Professor

The Royal Marsden NHS Foundation Trust
Sueery, United Kingdom
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