Last updated on September 2018

The Efficacy Safety and Pharmacokinetic of Antiplatelet Therapy for Vicagrel


Brief description of study

This is a multi-center, randomized, double-blind, triple-dummy, parallel-controled, dose-exploration phase II trial. Patients with coronary atherosclerotic heart disease and planned percutaneous coronary intervention PCI will be randomized after informed consent, in a 1:1:1:1 ratio to the following treatment groups: Experimental group 1 : Vicagrel 20mg loading followed by 5mg/day for 28 days; Experimental group 2 : Vicagrel 24mg loading followed by 6mg/day for 28 days; Experimental group 3 : Vicagrel 30mg loading followed by 7.5mg/day for 28 days; Control group : Clopidogrel 300mg loading followed by 75mg/day for 28 days. The primary purpose of this trial is to evaluate the efficacy, safety of vicagrel antiplatelet therapy and explore dose in patients with coronary atherosclerotic heart disease during and after PCI compared with clopidogrel.

Clinical Study Identifier: NCT03599284

Contact Investigators or Research Sites near you

Start Over

Ningru Zhang, MD

First Affiliated Hospital Bengbu Medical College
Bengbu, China
  Connect »

Jiyan Chen, MD

Guangdong General Hospital
Guangzhou, China
  Connect »

Yugang Dong, MD

First Affiliated Hospital of Zhongshan University
Guangzhou, China
  Connect »

Mingqi Zheng, MD

First Hospital of Hebei Medical University
Shijiazhuang, China
  Connect »

Xi Su, MD

Wuhan Asia Heart Hospital
Wuhan, China
  Connect »

Luping Jiang, MD

Changsha Central Hospital
Changsha, China
  Connect »

Zaixin Yu, MD

Xiangya Hospital of Central South University
Changsha, China
  Connect »

Daoquan Peng, MD

Second Xiangya Hospital of Central South University
Changsha, China
  Connect »

Yu Cao, MD

Third Xiangya Hospital of Central South University
Changsha, China
  Connect »

Biao Xu, MD

Affiliated Drum Tower Hospital of Nanjing University Medical School
Nanjing, China
  Connect »

Chengchun Tang, MD

Zhongda Hospital of Southeast University
Nanjing, China
  Connect »

Yu Tang, MD

Jiangxi Provincial People's Hospital
Nanchang, China
  Connect »

Yang Zheng, MD

First Hospital of Jilin University
Changchun, China
  Connect »

Bin Liu, MD

Second Hospital of Jilin University
Changchun, China
  Connect »

Yaling Han, MD

the General Hospital of Shenyang Military Region of The Chinese People's Liberation Army
Shenyang, China
  Connect »

Zhanquan Li, MD

The People's Hospital of Liaoning Province
Shenyang, China
  Connect »

Wenyue Pang, MD

Shengjing Hospital of China Medical University
Shenyang, China
  Connect »

Rong Chang, MD

Qinghai Provincial People's Hospital
Xining, China
  Connect »

Liuyi Hao, MD

Yuncheng Central Hospital
Yuncheng, China
  Connect »

Zhongcai Fan, MD

Affiliated Hospital of Southwest Medical University
Luzhou, China
  Connect »

Jianan Wang, MD

Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, China
  Connect »

Guosheng Fu, MD

Sir Run Run Shaw Hospital
Hangzhou, China
  Connect »

Hong Jiang, MD

China-Japan Friendship Hospital
Beijing, China
  Connect »

Shuyang Zhang, MD

Peking Union Medical College Hospital
Beijing, China
  Connect »

Yuemin Sun, MD

Tianjin Medical University General Hospital
Tianjing, China
  Connect »

Zhuhua Yao, MD

Tianjin People's Hospital
Tianjin, China
  Connect »