Last updated on September 2018

Impact of Open Lung Concept and Opioid Free Anesthesia on Post Operative Outcome.


Brief description of study

Opioids used intra operative increase the amount of opioids needed post operative to control post operative pain. if opioids are given post operative, we assume that more atelectasis and hypoxia takes place with or without open lung ventilation. Lower saturations will require giving more frequent oxygen.

Lung recruitment followed by positive end expiratory pressure (PEEP) keeps the lungs open during mechanical ventilation and can be verified by following the dynamic lung compliance. If patients are extubated with open lungs, we assume that they keep their lungs longer open post operative with or without getting opioids as measured by the requirement to give oxygen.

Detailed Study Description

this is an observational study where the attending anesthesiologist decides to use opioid free or opioid general anesthesia based on his/her expertise and decides also to use the open lung ventilation by giving a recruitment followed by high PEEP when lung compliance decreases below 40 ML/cmH20 again based on his/her expertise.

all patients will be followed by the intra operative lung compliance and the post operative oxygen saturation without adding oxygen therapy.

If post operative saturation drops below 95% oxygen therapy is given and noted.

Clinical Study Identifier: NCT03660306

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jan P mulier, PhD

Azsintjan
Brugge, Belgium
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