Last updated on September 2018

Acetaminophen Versus IV Hydromorphone for Pain in the Elderly in the ED


Brief description of study

Intravenous opioids are the mainstay of acute, severe pain treatment in Emergency Departments (ED) across the country. Acetaminophen, given orally, has also been used for treatment of mild to moderate pain. The more potent intravenous (IV) form of acetaminophen has been widely used in Europe for more than 20 years as post-surgical analgesia and received full FDA approval in the USA in 2010. As part of a continuing set of studies whose goal is to optimize treatment of pain among elderly ED patients, this randomized study will compare efficacy and safety of IV acetaminophen to IV hydromorphone.

Clinical Study Identifier: NCT03521102

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Benjamin W Friedman

Montefiore Medical Center
Bronx, NY United States
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