Last updated on August 2016

A Study of MM-121 in Combination With Chemotherapy Versus Chemotherapy Alone in Heregulin Positive NSCLC


Brief description of study

The purpose of this study is to determine whether the combination of MM-121 plus docetaxel or pemetrexed is more effective than docetaxel or pemetrexed alone in regards to OS in patients with heregulin-positive NSCLC.

Detailed Study Description

This study is a randomized, open-label, international, multi-center, phase 2 study in patients with Heregulin-positive NSCLC that have progressed following no more than three systemic therapies for locally advanced or metastatic disease, of which one must have been an anti-PD-1 or anti-PD-L1 therapy. All patients will initially be screened for heregulin status. Eligible patients will be randomized to receive MM-121 in combination with investigator's choice of either docetaxel or pemetrexed versus docetaxel or pemetrexed alone.

Clinical Study Identifier: NCT02387216

.

Contact Investigators or Research Sites near you

Start Over

Please choose location

View all locations

Patricia Plezia, PharmD

Tucson, AZ United States
  Connect »

Jorge Nieva, MD

Los Angeles, CA United States
  Connect »

Kimberly Young

Santa Rosa, CA United States
  Connect »

Angela Akar

Tampa, FL United States
  Connect »

Adrian Segura

Chicago, IL United States
  Connect »

Wael Harb, MD

Lafayette, IN United States
  Connect »

David Boucher

Boston, MA United States
  Connect »

Gayle Calistro

Danvers, MA United States
  Connect »

Haiying Cheng, MD

Bronx, NY United States
  Connect »

Jennifer Hull, RN

New York, NY United States
  Connect »

John Lee

Philadelphia, PA United States
  Connect »

Mara Yerk

Pittsburgh, PA United States
  Connect »

Karin Chocquette, RN

Fairfax, VA United States
  Connect »

Leila Ponce

Seattle, WA United States
  Connect »

Antonio Estacio

Toronto, ON Canada
  Connect »

Nancy Herrman

Bad Berka, Germany
  Connect »

Annegret Koepke

Frankfurt, Germany
  Connect »

Eniko Jambor

Budapest, Hungary
  Connect »

Monika Daruka

Miskolc, Hungary
  Connect »

Anna Keresztesi

Tatabanya, Hungary
  Connect »

Teresa Moran

Badalona, Spain
  Connect »