Last updated on October 2018

Study to Evaluate Efficacy and Safety of PF-04965842 With or Without Topical Medications in Subjects Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis


Brief description of study

B7451015 is a Phase 3 study to evaluate PF-04965842 with or without Topical Medications in patients aged 12 years and older with a minimum body weight of 40 kg who have moderate to severe atopic dermatitis and have completed a qualifying Phase 3 study. The efficacy and safety of two dosage strengths of PF-04965842, 100 mg and 200 mg taken orally once daily, will be evaluated over approximately two years of study participation. Patients who meet safety step-down criteria will have their dose reduced once, from 200 mg QD to 100 mg QD, or from 100 mg QD to placebo.

Clinical Study Identifier: NCT03422822

Contact Investigators or Research Sites near you

Start Over

Pfizer CT.gov Call Center

California Dermatology & Clinical Research Institute
Encinitas, CA United States
  Connect »

Pfizer CT.gov Call Center

Clinical Research Center of Alabama, LLC
Birmingham, AL United States
  Connect »

Pfizer CT.gov Call Center

Clinical Science Institute
Santa Monica, CA United States
  Connect »

Pfizer CT.gov Call Center

Florida Academic Centers Research and Education, LLC
Coral Gables, FL United States
  Connect »

Pfizer CT.gov Call Center

Forward Clinical Trials, Inc.
Tampa, FL United States
  Connect »

Pfizer CT.gov Call Center

NorthShore University HealthSystem Dermatology Clinical Trials Unit
Skokie, IL United States
  Connect »

Pfizer CT.gov Call Center

Dawes Fretzin Clinical Research Group, LLC
Indianapolis, IN United States
  Connect »

Pfizer CT.gov Call Center

Dawes Fretzin Dermatology Group, LLC
Indianapolis, IN United States
  Connect »

Pfizer CT.gov Call Center

Vital Prospects Clinical Research Institute, P.C.
Tulsa, OK United States
  Connect »

Pfizer CT.gov Call Center

Arlington Research Center, Inc.
Arlington, TX United States
  Connect »

Pfizer CT.gov Call Center

Tekton Research, Inc.
Austin, TX United States
  Connect »

Pfizer CT.gov Call Center

Virginia Clinical Research, Inc
Norfolk, VA United States
  Connect »

Pfizer CT.gov Call Center

Meridian Clinical Research, LLC
Savannah, GA United States
  Connect »

Pfizer CT.gov Call Center

Lynn Health Science Institute
Oklahoma City, OK United States
  Connect »

Pfizer CT.gov Call Center

Somerset Skin Centre
Troy, MI United States
  Connect »

Pfizer CT.gov Call Center

TCR Medical Corporation
San Diego, CA United States
  Connect »

Pfizer CT.gov Call Center

Australian Clinical Research Network
Maroubra, Australia
  Connect »

Pfizer CT.gov Call Center

Spectrum Medical Imaging
Maroubra, Australia
  Connect »

Pfizer CT.gov Call Center

Queensland X-Ray
Upper Mount Gravatt, Australia
  Connect »

Pfizer CT.gov Call Center

Veracity Clinical Research Pty Ltd
Woolloongabba, Australia
  Connect »

Pfizer CT.gov Call Center

Skin and Cancer Foundation Inc
Carlton, Australia
  Connect »

Pfizer CT.gov Call Center

Uniradiology
Carlton, Australia
  Connect »

Pfizer CT.gov Call Center

Meridian Clinical Research, LLC
Baton Rouge, LA United States
  Connect »

Pfizer CT.gov Call Center

Health Concepts
Rapid City, SD United States
  Connect »

Pfizer CT.gov Call Center

Sinclair Dermatology
East Melbourne, Australia
  Connect »

Pfizer CT.gov Call Center

Bridge Road Imaging
Richmond, Australia
  Connect »

Pfizer CT.gov Call Center

Southern California Dermatology, Inc.
Santa Ana, CA United States
  Connect »

Pfizer CT.gov Call Center

Baumann Cosmetic and Research Institute
Miami, FL United States
  Connect »

Pfizer CT.gov Call Center

Dermatologic Surgery Specialists, PC
Macon, GA United States
  Connect »

Pfizer CT.gov Call Center

Dermatology Treatment & Research Center, PA
Dallas, TX United States
  Connect »

Pfizer CT.gov Call Center

Dermatology Associates of Seattle
Seattle, WA United States
  Connect »

Pfizer CT.gov Call Center

Debreceni Egyetem Klinikai Kozpont
Debrecen, Hungary
  Connect »

Pfizer CT.gov Call Center

CRU Hungary Kft.
Miskolc, Hungary
  Connect »

Pfizer CT.gov Call Center

Total Skin and Beauty Dermatology Center, PC
Birmingham, AL United States
  Connect »

Pfizer CT.gov Call Center

Park Avenue Dermatology
Orange Park, FL United States
  Connect »

Pfizer CT.gov Call Center

Kansas City Dermatology, PA
Overland Park, KS United States
  Connect »

Pfizer CT.gov Call Center

Tufts Medical Center
Boston, MA United States
  Connect »

Pfizer CT.gov Call Center

Innovate Research, LLC
Fort Worth, TX United States
  Connect »

Pfizer CT.gov Call Center

Texas Dermatology and Laser Specialists
San Antonio, TX United States
  Connect »

Pfizer CT.gov Call Center

Pace Dermatology Associates
Lakewood, WA United States
  Connect »

Pfizer CT.gov Call Center

Dermatology Specialists of Spokane
Spokane, WA United States
  Connect »

Pfizer CT.gov Call Center

MultiCare Allenmore Hospital
Tacoma, WA United States
  Connect »

Pfizer CT.gov Call Center

MultiCare Institute for Research and Innovation
Tacoma, WA United States
  Connect »

Pfizer CT.gov Call Center

Pace Dermatology Associates
Tacoma, WA United States
  Connect »

Pfizer CT.gov Call Center

Innovaderm Research Inc.
Montreal, QC Canada
  Connect »

Pfizer CT.gov Call Center

Bacs-Kiskun Megyei Korhaz Szegedi Tudomanyegyetem AOK Oktatokorhaza, Borgyogyaszati Osztaly
Kecskemet, Hungary
  Connect »

Pfizer CT.gov Call Center

Pecsi Tudomanyegyetem Klinikai Kozpont, Bor-,Nemikortani es Onkodermatologiai Klinika
Pecs, Hungary
  Connect »

Pfizer CT.gov Call Center

Pro Familia Altera Sp. z o.o.
Katowice, Poland
  Connect »

Pfizer CT.gov Call Center

Dermedic Jacek Zdybski
Ostrowiec Swietokrzyski, Poland
  Connect »

Pfizer CT.gov Call Center

Dermatology Specialists, Inc.
Oceanside, CA United States
  Connect »

Pfizer CT.gov Call Center

Forest Hills Dermatology Group
Forest Hills, NY United States
  Connect »

Pfizer CT.gov Call Center

Oregon Medical Research Center
Portland, OR United States
  Connect »

Pfizer CT.gov Call Center

Emeritus Research
Camberwell, Australia
  Connect »

Pfizer CT.gov Call Center

MIA Radiology
Camberwell, Australia
  Connect »

Pfizer CT.gov Call Center

MULTIKLINIKA Salute Sp. z o.o.
Katowice, Poland
  Connect »

Pfizer CT.gov Call Center

Silmedic Sp. z o.o., Oddzial w Katowicach
Katowice, Poland
  Connect »

Pfizer CT.gov Call Center

Centrum Medyczne Angelius Provita
Katowice, Poland
  Connect »

Pfizer CT.gov Call Center

Dermoklinika-Centrum Medyczne s.c. M. Kierstan, J. Narbutt, A. Lesiak
Lodz, Poland
  Connect »

Pfizer CT.gov Call Center

Olympian Clinical Research
Largo, FL United States
  Connect »

Pfizer CT.gov Call Center

Sadick Research Group, LLC
New York, NY United States
  Connect »

Pfizer CT.gov Call Center

Center for Dermatology Clinical Research, Inc.
Fremont, CA United States
  Connect »

Pfizer CT.gov Call Center

Mosaic Dermatology
Santa Monica, CA United States
  Connect »

Pfizer CT.gov Call Center

Olympian Clinical Research
Clearwater, FL United States
  Connect »

Pfizer CT.gov Call Center

Skin Research Institute
Coral Gables, FL United States
  Connect »

Pfizer CT.gov Call Center

Clinical Neuroscience Solutions, Inc.
Orlando, FL United States
  Connect »

Pfizer CT.gov Call Center

ASR, LLC
Nampa, ID United States
  Connect »

Pfizer CT.gov Call Center

Midwest Allergy Sinus Asthma, SC
Normal, IL United States
  Connect »

Pfizer CT.gov Call Center

The Indiana Clinical Trials Center
Plainfield, IN United States
  Connect »

Pfizer CT.gov Call Center

Henry Ford Medical Center, New Center One
Detroit, MI United States
  Connect »

Pfizer CT.gov Call Center

M3-Wake Research, Inc.
Raleigh, NC United States
  Connect »

Pfizer CT.gov Call Center

PMG Research of Wilmington, LLC
Wilmington, NC United States
  Connect »

Pfizer CT.gov Call Center

Wilmington Health Family Medicine (X-Ray only)
Wilmington, NC United States
  Connect »

Pfizer CT.gov Call Center

Dermatologists of Greater Columbus
Bexley, OH United States
  Connect »

Pfizer CT.gov Call Center

Newton Clinical Research
Oklahoma City, OK United States
  Connect »

Pfizer CT.gov Call Center

Paddington Testing Co, Inc.
Philadelphia, PA United States
  Connect »

Pfizer CT.gov Call Center

Ventavia Research Group
Hurst, TX United States
  Connect »

Pfizer CT.gov Call Center

Tien Q Nguyen MD Inc dba First OC Dermatology
Fountain Valley, CA United States
  Connect »

Pfizer CT.gov Call Center

Allergy & Asthma Care Center of Southern California
Long Beach, CA United States
  Connect »

Pfizer CT.gov Call Center

San Luis Dermatology and Laser Clinic
San Luis Obispo, CA United States
  Connect »

Pfizer CT.gov Call Center

Skin Care Research, LLC
Boca Raton, FL United States
  Connect »

Pfizer CT.gov Call Center

Clinical Neuroscience Solutions, Inc.
Jacksonville, FL United States
  Connect »

Pfizer CT.gov Call Center

Ds Research
New Albany, IN United States
  Connect »

Pfizer CT.gov Call Center

Wiseman Dermatology Research Inc.
Winnipeg, MB Canada
  Connect »

Pfizer CT.gov Call Center

Lynderm Research Inc.
Markham, ON Canada
  Connect »

Pfizer CT.gov Call Center

The Centre for Dermatology
Richmond Hill, ON Canada
  Connect »

Pfizer CT.gov Call Center

York Dermatology Center
Richmond Hill, ON Canada
  Connect »

Pfizer CT.gov Call Center

Universit tsklinikum Erlangen
Erlangen, Germany
  Connect »

Pfizer CT.gov Call Center

Universitaetsklinikum Schleswig-Holstein, Campus Kiel
Kiel, Germany
  Connect »

Pfizer CT.gov Call Center

Ludwig-Maximilians-University Munich
Munich, Germany
  Connect »

Pfizer CT.gov Call Center

Klinische Forschung Schwerin GmbH
Schwerin, Germany
  Connect »

Pfizer CT.gov Call Center

Solutions Through Advanced Research, Inc.
Jacksonville, FL United States
  Connect »

Pfizer CT.gov Call Center

Tanenbaum Dermatology Center
Memphis, TN United States
  Connect »

Pfizer CT.gov Call Center

Clinical Neuroscience Solutions, Inc.
Memphis, TN United States
  Connect »

Pfizer CT.gov Call Center

Austin Institute for Clinical Research, Inc. - Central
Austin, TX United States
  Connect »

Pfizer CT.gov Call Center

Dr. Chih-ho Hong Medical Inc
Surrey, BC Canada
  Connect »

Pfizer CT.gov Call Center

SKiN Centre for Dermatology
Peterborough, ON Canada
  Connect »

Pfizer CT.gov Call Center

Lekarna Na Vaclavskem namesti
Kutna Hora, Czechia
  Connect »

Pfizer CT.gov Call Center

Kozni ambulance Kutna Hora, s.r.o.
Kutna Hora, Czechia
  Connect »

Pfizer CT.gov Call Center

Sanatorium profesora Arenbergera
Praha 1, Czechia
  Connect »

Pfizer CT.gov Call Center

Lekarna U sv. Ignace
Praha 2, Czechia
  Connect »

Pfizer CT.gov Call Center

Krajska zdravotni a.s., Masarykova nemocnice o.z.
Usti nad Labem, Czechia
  Connect »

Pfizer CT.gov Call Center

Lekarna Masarykovy nemocnice v Usti nad Labem, o.z.
Usti nad Labem, Czechia
  Connect »

Pfizer CT.gov Call Center

NZOZ "DERMED" Centrum Medyczne Sp. z o.o. - Oddzial w Lodzi
Lodz, Poland
  Connect »