Last updated on April 2018

Invasive Pulmonary Aspergillosis Complicating Influenza Infection


Brief description of study

Study the incidence and outcome of invasive pulmonary aspergillosis (IPA) in ICU patients with severe influenza and in influenza-negative control patients with severe community-acquired pneumonia

Detailed Study Description

This prospective multicentre case-control registration study in Dutch and Belgian ICUs will assess the difference in incidence and outcome of invasive pulmonary aspergillosis (IPA) in ICU patients with severe influenza compared with influenza-negative control patients with severe community-acquired pneumonia during the coming three influenza seasons (2017-2020). The study will further assess the differences in clinical characteristics and risk factors between influenza patients with and without invasive aspergillosis.

All consecutive patients aged 18 or older admitted to ICU during the inclusion period with respiratory distress due to influenza positive/negative community acquired pneumonia (CAP) will be included.

Clinical Study Identifier: NCT03391492

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Marc Bourgeois, PhD

AZ sint Jan
Brugge, Belgium
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Petere Messiaen, Phd

Jessa AH
Hasselt, Belgium
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