Last updated on November 2016

HIV UPBEAT: Understanding the Pathology of Bone Disease in HIV-infected Patients.


Brief description of study

Despite the prevalence of osteopenia and osteoporosis in the HIV positive population, relatively little is known about the underlying pathology. This prospective cohort study aims to gain further understanding about a number of issues relating to low bone mineral density in HIV-infected subjects.

Detailed Study Description

This study will follow HIV positive and negative subjects annually for 5 years. The aims of this study include: - to describe the pathology underlying low bone mineral density - to assess the relationship between low bone mineral density and antiretroviral therapy exposure - to assess the relationship between low bone mineral density and vitamin D /PTH status and/or markers of bone metabolism - to assess the relationship between osteopenia and subsequent changes in bone mineral density and markers of bone metabolism - to assess the validity of the currently available fracture risk assessment tool in predicting fractures in HIV positive populations

Clinical Study Identifier: NCT01778361

.

Contact Investigators or Research Sites near you

Start Over

Please choose location

View all locations

Patrick WG Mallon, MB BCh, ...

Mater Misericordiae University Hospital
Dublin, Ireland
  Connect »