Last updated on February 2018

Does Vitamin D Break the Vicious Circle of Polycystic Ovarian Syndrome of Insuline Resistance ?


Brief description of study

Recently, a special emphasis has recently been directed to the potential role of vitamin D and some regulatory peptides (e.g. adipokines and follistatin) and their associated metabolic roles and genetic factors in the development of PCOS and its related co-morbidities. The aim of this study is to compare the effect of vitamin D supplementation therapy and Metformin therapy on plasma concentrations of adipokines (ghrelin, resistin and adiponectin), follistatin and activins in participants diagnosed with PCOS.

Detailed Study Description

Research question:

In PCOS patients, is there any effect of vitamin D supplementation therapy on plasma concentrations of adipokines (ghrelin, resistin and adiponectin), follistatin and activins?

Research hypothesis:

There is a significant effect of vitamin D supplementation therapy on plasma concentrations of adipokines (ghrelin, resistin and adiponectin), follistatin and activin.

Clinical Study Identifier: NCT02656121

Contact Investigators or Research Sites near you

Start Over

ahmed kotb, MD

Faculty of Medicine, Ain Shams University
Cairo, Egypt
  Connect »