Last updated on February 2018

International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)


Brief description of study

Multicentric, international, web-based prospective documentation of the indications and results of Pressurized Aerosol Chemotherapy (so-called PIPAC or PITAC) for treating malignant pleural and peritoneal diseases. Indication is decided by the treating physician. There are no predefined inclusion or exclusion criteria.

Detailed Study Description

All data entered into the registry documenting the patient cohort characteristics (disease, demography, therapy) are analyzed using descriptive statistics. Survival data are analyzed with Kaplan-Meier statistics. Multivariate Cox Proportional Hazard Models are used to identify potential prognostic and predictive factors. In particular, a risk- adjusted comparison of the outcome criteria with a propensity score is planned.

The data are stored in a SQL-based online database. Patient data are pseudoanonymized. The registry has received approval of the data protection officer of the State of Northrhine-Westphalia.

The study steering committee is blinded towards the identity of the participating institutions. Each participating institution receives an annual report with own data vs. benchmark. Scientific analysis can be proposed by the steering committee, by a participating institution or by other scientists, subjected to the approval of the independent scientific advisory board.

An export function has been built in to allow data exchange with the HIPEC Registry of the German Society for General and GI surgery (http://www.dgav.de/studoq/studoqhipec.html).

Clinical Study Identifier: NCT03210298

Contact Investigators or Research Sites near you

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Laura Lay, MD

Roffo Cancer Institute
Buenos Aires, Argentina
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Craig Lynch, MD

Peter MacCallum Cancer Centre
Melbourne, Australia
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Woulter Willaert, MD

University Hospital Gent (UZ Gent)
Gent, Belgium
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Martin Graversen, MD

University Hospital Odense
Odense, Denmark
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Olivier Glehen, MD

Hospices civils de Lyon
Lyon, France
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Clarisse Eveno, MD

H pital Lariboisi re
Paris, France
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Verena Schlaich

University Hospital T bingen
Tübingen, Germany
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Aditi Bhatt, MD

Fortis Hospital
Bengaluru, India
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Marco Vaira, MD

IRCC Torino Candiolo
Turin, Italy
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Maciej Nowacki, MD

F. ukaszczyk Oncology Centre
Bydgoszcz, Poland
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Vladimir Khomyakov, MD

Gersten Institute for Cancer Research
Moscow, Russian Federation
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Janelle Phua

National University Hospital
Singapore, Singapore
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Juan Torrent, MD

Hospital de Pilar
Barcelona, Spain
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Martin Huebner, MD

University Hospital Lausanne CHUV
Lausanne, Switzerland
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