Last updated on February 2018

Total Antioxidant Capacity Before and After HRT in Hypotalamic Amenorrhea


Brief description of study

The aim of our study is to investigate the effects of 6 months oh HRT on total anti-oxidant capacity, clinical, endocrine and metabolic features in women affected by hypotalamic amenorrhea. The study group included 20 patients treated with 1 mg of transdermal estradiol daily and 10mg of oral Medroxyprogesterone acetate from 16th to 24th day of therapy for six months. Menstrual pattern, anthropometric parameters, hormonal assays, DXA and bone metabolism parameters are evaluated before and after therapy.

Clinical Study Identifier: NCT02984696

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Rosanna Apa, MD

Catholic university of Sacred Heart
Rome, Italy
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