Last updated on February 2018

Assessing the Efficacy of Clomiphene Citrate in Patients With Azoospermia and Hypoandrogenism


Brief description of study

Hypothesis: Prescribed clomiphene citrate to azoospermic patients with hypoandrogenism could improve the sperm retrieval in either fresh sperm or after surgical sperm extraction.

Detailed Study Description

Hypogonadism (low testosterone level) is frequently observed in men presenting with non obstructive azoospermia. Controversy exists regarding the efficacy of preoperative hormonal manipulation in patients with hypogonadism. However, it is possible that hormonal therapy increases intra-testicular testosterone levels, and with a rise in serum testosterone, sperm production and surgical success with microTESE improve.

Clinical Study Identifier: NCT02137265

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Satur Luján, MD, PhD

University of Valencia
Valencia, Spain
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