Last updated on February 2018

Adjuvant Chemotherapy for High-risk Retinoblastoma After Enucleation


Brief description of study

The purpose of this study is to determine whether 3 cycles of chemotherapy(CEV) are as effective as 6 cycles of chemotherapy(CEV) in the treatment of Stage I enucleated retinoblastoma.

Detailed Study Description

This study will be a phase open label interventional case series. Patients with Stage I enucleated retinoblastoma will be randomized to receive chemotherapy(CEV) of 3 cycles or 6 cycles on a monthly basis. Patients will be followed for 24 months.

Clinical Study Identifier: NCT01906814

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Huasheng Yang, M.D, PHD

Zhongshan Ophthalmic Center, Sun Yat-sen University
Guangzhou, China
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