Last updated on September 2018

Study to Evaluate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years And Older With Moderate to Severe Atopic Dermatitis


Brief description of study

B7451012 is a Phase 3 study to evaluate PF-04965842 in patients aged 12 years and older with a minimum body weight of 40 kg who have moderate to severe atopic dermatitis. The efficacy and safety of two dosage strengths of PF-04965842, 100 mg and 200 mg taken orally once daily, will be evaluated relative to placebo over 12 weeks of study participation. Eligible patients will have an option to enter a long-term extension study after completing 12 weeks of treatment.

Clinical Study Identifier: NCT03349060

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Clinical Research Center of Alabama, LLC
Birmingham, AL United States
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California Dermatology & Clinical Research Institute
Encinitas, CA United States
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Clinical Science Institute
Santa Monica, CA United States
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Forward Clinical Trials, Inc.
Tampa, FL United States
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Tulsa, OK United States
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Saint Joseph, MO United States
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Lynn Health Science Institute
Oklahoma City, OK United States
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Tekton Research, Inc.
Austin, TX United States
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Texas Dermatology and Laser Specialists
San Antonio, TX United States
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Virginia Clinical Research, Inc.
Norfolk, VA United States
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Somerset Skin Centre
Troy, MI United States
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TCR Medical Corporation
San Diego, CA United States
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Florida Academic Centers Research and Education, LLC
Coral Gables, FL United States
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Arlington Research Center, Inc.
Arlington, TX United States
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Pace Dermatology Associates
Lakewood, WA United States
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MultiCare Allenmore Hospital
Tacoma, WA United States
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MultiCare Institute for Research and Innovation
Tacoma, WA United States
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Pace Dermatology Associates
Tacoma, WA United States
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Dawes Fretzin Clinical Research Group, LLC
Indianapolis, IN United States
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Dawes Fretzin Dermatology Group, LLC
Indianapolis, IN United States
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Olympian Clinical Research
Largo, FL United States
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NorthShore University HealthSystem Dermatology Clinical Trials Unit
Skokie, IL United States
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Australian Clinical Research Network
Maroubra, Australia
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Spectrum Medical Imaging
Maroubra, Australia
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Innovaderm Research Inc.
Montreal, QC Canada
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Diex Research Sherbrooke Inc.
Sherbrooke, QC Canada
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Sinclair Dermatology
East Melbourne, Australia
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Bridge Road Imaging
Richmond, Australia
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CRU Hungary Ltd.
Miskolc, Hungary
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Tufts Medical Center
Boston, MA United States
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Henry Ford Medical Center, New Center One
Detroit, MI United States
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Emeritus Research
Camberwell, Australia
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MIA Radiology
Camberwell, Australia
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Skin and Cancer Foundation Inc
Carlton, Australia
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Uniradiology
Carlton, Australia
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Kirk Barber Research
Calgary, AB Canada
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Dr. Chih-ho Hong Medical Inc
Surrey, BC Canada
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The Centre for Dermatology
Richmond Hill, ON Canada
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York Dermatology Center
Richmond Hill, ON Canada
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Fachklinik Bad Bentheim
Bad Bentheim, Germany
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ISA - Interdisciplinary Study Association GmbH
Berlin, Germany
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Universit tsklinikum Erlangen, Hautklinik
Erlangen, Germany
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Munich, Germany
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Schwerin, Germany
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Debreceni Egyetem Klinikai Kozpont Borgyogyaszati Klinika
Debrecen, Hungary
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Kecskemet, Hungary
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Pecs, Hungary
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Upper Mount Gravatt, Australia
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Woolloongabba, Australia
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Peterborough, ON Canada
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Markham, ON Canada
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Calgary, AB Canada
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Winnipeg, MB Canada
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University of British Columbia Department of Dermatology and Skin Science
Vancouver, BC Canada
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Providence, RI United States
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Lodz, Poland
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Ostrowiec Swietokrzyski, Poland
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Charleston, SC United States
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