Last updated on February 2018

SQUED Series 28.1 Home-use and Treatment of Autowave Reverberator of Autism


Brief description of study

Locomotor, transport and information functions in human body systems are carried out by active media in autowave regimes! Any living organism is a (micro-macro-mega) hierarchy of autowave subsystems-an ensemble of loosely coupled subsystems of a simpler structure. From the highest levels of the hierarchy, Autowave Codes-Signals arrive, which determine the transitions of subsystems from one autowave regime to another Autowave interaction (of Complex Coherent Action). Autowave interaction is a process associated with the evolution and interaction of spatial and wave structures in the active media of the organism.

Chaos in organism functioning tells about health. Periodicity - Autowave reverberator may presage a disease - Autism Spectrum Disorder; Chaotic nature of oscillations in active media of physiological systems is more optimal for their vital functions than periodic one. Firstly, systems that function in chaotic regimes, can re-arrange themselves faster and easier in case of change of environmental conditions, i.e. the so called adaptive control is more easily implemented in them. Secondly, "spreading" of oscillations strength along comparatively wide frequency band takes place in chaotic regime.

When an organism is young and healthy, physiological systems show the elements of chaotic behavior, i.e. irregularity and chaotic dynamics are the extremely important characteristics of health. Decrease in changeability and appearance of stable periodicity of Autowave reverberator are often connected with Autism.

The main purpose is to study brain plasticity (the changes that occur in the brain through Autowave reverberator) in children with autism. Research suggests that during development, the brains of children may change in response to their Autowave reverberator differently than the brains of typically developing individuals. Investigators want to understand why and how this difference may contribute to the symptoms of autism spectrum disorder (ASD). In this study, the investigators will be examining the effects of non-invasive neuromodulation SQUED series 28.1 home-use for Treatment of Autowave reverberator of Autism.

Integrative Team World Organization of Medical Synergetics (WOMS) - collaborations between physicians and researchers with expertise in biostatistics, physics, mathematics, engineering, and computer science.

Detailed Study Description

Autowave Reverberator:

  1. Proved that, a Autowave Reverberator appears a result of a rupture of Autowave front; initial conditions - Natal Trauma:
     1.1 Proved that, such a rupture may occur, via collision of the Autowave front with a
     nonexcitable obstacle - brain injury or injury of vertebral;

     1.2 Proved that, such a rupture may occur by loss of excitation in a certain region of
     the Active medium - cerebral anoxia;

     1.3 Locomotor, Transport and Information functions in the physiological systems, and
     Communicative Efforts, Speech, Language and Related Cognitive Functions this is Autowave
     processes in Active media.

2. An important feature of reverberators is that these Autowave sources have the highest

     frequency. By generating pulses at a maximum frequency such sources force out
     self-pacemakers of any other types from the medium. As a result, the Active medium is
     filled with only Spiral Autowaves:

     2.1 The basic parameters of a reverberator are the frequency of generated waves, the
     critical dimension and characteristics of the structure of the kernel, and the velocity
     of the kernel in space, at Drift of Spiral Autowaves and/or Annihilation of Spiral
     Autowaves, or Multiplication of Spiral Autowaves;

     2.2 Commonly, there are two characteristic regions in a reverberator: a kernel having an
     excitation "tongue" entering it and Spiral Autowaves generated by the kernel - one
     spiral/two spirals/three spirals/four spirals; central filament of the Autowaves-branch
     rotates Left/Right;

     2.3 The kernel can have the form of a circle or a ring, a so-called "anomalous" kernel.
     If the source drifts, the form of the kernel is involved and can hardly be determined
     unambiguously.

3. Proved that, the reverberator is not tied to any structure in the Active medium:

     3.1 Proved that, due to this property, reverberators can Appear and Disappear in the
     different Endoderm/Mesoderm/Ectoderm of the Active media, and at different locations of
     the Active medium;

     3.2 Proved that, due to this property, reverberators can Appear and Disappear in the
     Ectodermal Active media - Brain/spinal cord/hair/Skin; central filament of the
     endogenous Brain branch/exogenous Skin-branch;

     3.3 Proved that, reverberators can Observe on the skin, Spiral Autowaves generated by
     the kernel - one spiral/two spirals/three spirals/four spirals; central filament of the
     Pileous-branch rotates Left/Right.

4. Proved, Center of Synergetics/Dr. Synergetic (the name of a new physician - Nonlinear

     Control of Autowaves chaos in Active media), Nonlinear Control of Autowaves
     reverberators:

     4.1 Proved, Nonlinear Control of Autowaves reverberators: Hysteresis of Spiral
     Autowaves, Drift of Spiral Autowaves and Annihilation of Spiral Autowaves.

5. Treatment of Autowave Reverberator of Autism (this will be administered by Presence of Clinical protocol CRF-SQUED):

5.1 Diagnostics of Autowave reverberators and Mathematical Modeling of Autowave reverberators in Active media + Algorithmic approach;

5.2 Computational Simulation of Autowave reverberator and Mathematical Modeling of treatment code (Trade Secret) + creation Active medium SQUED for a patient;

5.3 Recording for a patient of treatment code (Trade Secret) on the Image Converter/Sound Converter/Electromagnetic Converter + Autowave regime: Hysteresis of Spiral Autowaves; Drift of Spiral Autowaves; Annihilation of Autowave reverberator;

5.4 SQUED Treatment of Autowave reverberator of Autism (Novel type energy/Non-invasive) + Semiconducting Quantum Excitonic Device - artificial active medium, where the processes of self-organization lead to creation and converter of Autowaves energy.

Some autowaves have the properties of quasi-particles!

Participants in the study will be asked to do the following things:

  • Grant permission for the researchers to view medical/psychological and/or educational and/or speech records associated with the diagnosis of autism.
  • Complete a questionnaire and provide a health history.
  • Complete evaluations by our study team to assess the diagnosis and gain a clearer understanding of the participant's current functioning.
  • Give to our study team of Photo of Autowave Reverberator - Presence on the Skin of the interruption of Autowave front (interruption of hair separatrix - dorsal/ventral) and/or Photo of Spiral Autowaves, generated by the kernel of Autowave Reverberator - the kernel having an excitation "tongue".
  • Give to our study team of Graphics on tracing paper of Autowave Reverberator - Presence on the Skin of the interruption of Autowave front (interruption of hair separatrix - dorsal/ventral) and/or Graphics on tracing paper of Spiral Autowaves, generated by the kernel of Autowave Reverberator - the kernel having an excitation "tongue".
  • Complete several tasks and training interventions that involve such things as learning new words or pictures, saying words out loud, or naming objects.
  • Complete several tasks and training interventions that involve such things as creation pictures iSQUED and music compositions sSQUED.
  • Give permission to audio and video-tape test sessions for later scoring and observation.
  • Give permission to audio or video-tape in the Home environment or classroom using non-intrusive audio-visual recording devices.
  • Participate in computerized tasks of Image converter SQUED (iSQUED). The software/device poses no risk and is non-invasive.
  • Participate in computerized tasks of Sound converter SQUED (sSQUED). The software/device poses no risk and is non-invasive.
  • Participate in computerized tasks of Electromagnetic converter SQUED (eSQUED). The device/software poses no risk and is non-invasive.

Clinical Study Identifier: NCT03222375

Contact Investigators or Research Sites near you

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Yuliya Yaroshuk, M.D.s. Ph.D., Asso. ...

World Autism Center, American Federation of Medical Synergetics, Department of Neurology; Cognitive Neurology/Neuropsychology WOMS
Louisville, KY United States
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Yuriy Fihol, M.D.s. Ph.D., Asso. ...

Clinic of Synergetics, Department of Neurology; Cognitive Neurology/Neuropsychology of the World Organization of Medical Synergetics
Lviv, Ukraine
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