Last updated on May 2010

Effect of Resveratrol on Age-related Insulin Resistance and Inflammation in Humans


Brief description of study

Effect of Resveratrol on Age-related Insulin Resistance and Inflammation in Humans

Detailed Study Description

Doctors at Albert Einstein College of Medicine are seeking overweight men and women, 45-65 years old, to participate in a research study to help understand resveratrol, a nutritional supplement found in red wine and berries, in order to see if it reduces the risk of diabetes. Free diabetes testing will be provided.

Patient Inclusion Criteria:

  • Male and female
  • Age: 45-65 yrs
  • BMI: 26-35
  • Non-smokers
  • Family history of diabetes (ideal, but not required)
  • Ideally no hypertension, but we may consider someone with well-controlled hypertension (on one medication only, at max. if they currently have normal blood pressure)

Patient Exclusion Criteria:
History of:

  • DM
  • High cholesterol
  • Severe hypertension
  • Heart disease
  • Liver disease or liver abnormalities
  • Cerebrovascular disease, i.e. stroke
  • CVD
  • Seizures
  • Bleeding disorders
  • Muscle disease
  • Cancer
  • HIV
  • Hepatitis (all types)
  • Mentally disabled persons
  • Pregnant women
  • Allergies to Novocaine, Lidocaine, Benzocaine
  • Subjects on the following medications:
    • Anticoagulant and antiplatelet drugs
    • Anti-epileptic drugs
    • Mexilitene
    • Quinidine
    • Cyclosporine
    • Tacrolimus
    • HIV protease inhibitors

Clinical Study Identifier: TX134877

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Morgan Drucker

The Harold & Muriel Block Institute for Clinical and Translational Research at Einstein & Montefiore
Bronx, NY USA
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