Last updated on July 2015

Efficacy of Oral Famciclovir Versus Aciclovir Treatment in Patients With Herpes Zoster


Brief description of study

Herpes Zoster is an infection that affects part of the nervous system caused by Varicella Zoster Virus. Herpes Zoster manifests as vesicular eruption in the dermatome, often associated with significant pain. There are effective oral prescription antiviral medicines available to reduce the discomfort of symptoms as famciclovir and aciclovir. This is a phase III, multicenter, randomized, parallel-group study to compare the efficacy and safety of treatment with Famciclovir (500 mg) comparing to Aciclovir (400 mg) in patients with Herpes Zoster.

Detailed Study Description

Study Design - Open-label, prospective, parallel group, intent to treat trial - Experiment duration: 7 days - 2 visits (days 0, and 7) - Reduction of symptoms - Adverse events evaluation

Clinical Study Identifier: NCT01327144

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Carlos Isaia Filho, MD

Centro de Medicina Reprodutiva Dr Carlos Isaia Filho
Porto Alegre, Brazil
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Fabio R Santos, MD

Loema
Campinas, Brazil
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Paula U. Tokunaga, MD

CECIP Centro de Estudos Cl nicos do Interior Paulista
Jau, Brazil
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Jane Tomimori, MD

Afip - Associacao Fundo de Incentivo A Pesquisa
Sao Paulo, Brazil
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André L Vergnanini, MD

Allergisa
Campinas, Brazil
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