Last updated on September 2018

A Study That Compares the Extent to Which Apomorphine Becomes Available in the Body After Taking Either an Investigational Drug Containing Apomorphine or Apomorphine That is Injected Under the Skin in People With PD Complicated by "OFF" Episodes

Brief description of study

A study that compares the extent to which apomorphine becomes available in the body after taking either an investigational drug containing apomorphine or apomorphine that is injected under the skin in people with PD complicated by "OFF" episodes.

Detailed Study Description

This multi-center study will aim to evaluate the pharmacokinetics (PK) and comparative bioavailability of a single dose of APL-130277 sublingual thin film with subcutaneous (s.c.) APO-go and s.c. APOKYN in subjects with Parkinson's disease (PD). The dose of APOKYN ( 5 mg) will be based on the subjects' current prescribed dose. The study is designed as an open-label, randomized, three-way crossover. Subjects will receive all three treatment arms with a minimum 1-day wash-out between each visit (excluding the screening visit) and will be randomly assigned to one of the six sequences

Clinical Study Identifier: NCT03292016

Contact Investigators or Research Sites near you

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Ramon Gil, MD

Parkinson's Disese Treatment Center of SW Florida
Port Charlotte, FL United States
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Aaron Ellenbogen, DO

QUEST Research Institute
Farmington Hills, MI United States
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