Last updated on June 2018

A Depot Formulation of Sunitinib Malate (GB-102) in Subjects With Neovascular (Wet) Age-related Macular Degeneration


Brief description of study

The purpose of this study is to evaluate the safety and efficacy of single and repeated intravitreal injections of GB-102 in subjects with neovascular (wet) age-related macular degeneration.

Detailed Study Description

In this 2-part study, Part 1 is a multicenter, open-label, safety, tolerability, and systemic exposure evaluation to Sunitinib in escalating doses of a single IVT injection of GB-102, while Part 2 is a multicenter, double-masked, randomized (1:1:1), parallelgroup, safety, and efficacy evaluation of repeated IVT injections of 2 dose levels of GB102 compared with aflibercept.

Clinical Study Identifier: NCT03249740

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Elisa Martinez

Retinal Consultants of Arizona
Gilbert, AZ United States
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Valentina Bozikovic

Retina Institute of California
Arcadia, CA United States
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Janet Kurokouch

Retina-Vitreous Associates Medical Group
Beverly Hills, CA United States
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Cari Novak

Midwest Eye Institute
Indianapolis, IN United States
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Courtney Wheeler

Retina Research Institute of Texas
Abilene, TX United States
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Michelle Curry

Texas Retina Associates
Arlington, TX United States
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VP, Global Clinical Development Operations

Retina Macula Specialists of Miami, LLC
Miami, FL United States
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Isabel Lezcano

Ophthalmic Consultants of Long Island
Lynbrook, NY United States
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Ivana Gunderson

Retina Research Center, PLLC
Austin, TX United States
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Beatrice Guajardo

Medical Center Ophthalmology Associates
San Antonio, TX United States
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