Last updated on April 2018

ADDIA Proof-of-Performance Clinical Study

Brief description of study

The objective of the ADDIA clinical Proof-of-Performance study is to validate the performance of ADDIA' blood biomarkers for diagnosis of Alzheimer's disease.

ADDIA clinical study is a multi-centre, non-interventional, prospective, proof-of-performance study with only one visit.

About 800 well-characterized subjects will be recruited into 3 groups in 2:1:1 ratio, namely patients with Alzheimer's disease (AD), patients with non-AD neurodegenerative disease (NAD) and 200 control subjects (healthy as compared to their age).

  • 400 patients with Alzheimer's disease (AD): 200 patients with mild AD, 200 patients with moderate-to-severe AD,
  • 200 patients with non-Alzheimer's neurodegenerative diseases (NAD),
  • 200 controls (healthy as compared to their age).

Clinical Study Identifier: NCT03030586

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Frédéric Blanc, MD

Hopitaux Universitaires de Strasbourg
Strasbourg, France
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Florence Pasquier, MD

Centre Hospitalier R gional Universitaire de Lille
Lille, France
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Moira Marizzoni, PhD

IRCCS Centro San Giovanni di Dio Fatenenefratelli
Brescia, Italy
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Jean-François Démonet, MD

Centre Hospitalier Universitaire Vaudois
Lausanne, Switzerland
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Hakan Gurvit, MD

Istanbul University Hospital
Istanbul, Turkey
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François Sellal, MD

H pitaux Civils (Hopital Louis Pasteur) de Colmar
Colmar, France
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Bruno Dubois, MD

APHP-H pitaux Universitaires Piti Salp tri re
Paris, France
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Adrian Ivanoiu, MD

Cliniques Universitaires Saint-Luc
Brussels, Belgium
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Jean-Christophe Bier, MD

ERASME Hospital
Brussels, Belgium
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Audrey Gabelle, MD

Centre Hospitalier Universitaire de Montpellier
Montpellier, France
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Saliha Moussaoui, PhD

Centre Hospitalier Universitaire de Nice
Nice, France
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Saliha Moussaoui, PhD

Centre Hospitalier Universitaire de Besan on
Besançon, France
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Giovanni Frisoni, MD

H pitaux Universitaires de Gen ve
Genève, Switzerland
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