Last updated on April 2018

Open-Label Multi-Center Two-Part Ph1 Study to Characterize the PKs of an Intravenous Micro-Dose of [14C]-Tazemetostat (EPZ 6438) and the ADME of an Oral [14C]-Labeled Dose of Tazemetostat in Subjects With B-Cell Lymphomas or Adv Solid Tumors

Brief description of study

This is a Phase 1, open-label, two-part study designed to characterize the PK of an IV dose of approximately 12 g tazemetostat that contains approximately 500 nCi of [14C] tazemetostat and the ADME of an oral dose of 800 mg tazemetostat that contains approximately 400 Ci of [14C]-labeled tazemetostat in three subjects with B-cell lymphomas or advanced solid tumors.

Clinical Study Identifier: NCT03010982

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Melissa Beelen

The Clatterbridge Cancer Centre NHS Foundation Trust
Bebington, United Kingdom
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Melissa Beelen

Royal Liverpool and Broadgreen University Hospital Trust
Liverpool, United Kingdom
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