Last updated on February 2017

HuMax-AXL-ADC Safety Study in Patients With Solid Tumors


Brief description of study

The purpose of the trial is to establish the tolerability of HuMax-AXL-ADC in a mixed population of patients with specified solid tumors

Detailed Study Description

The trial consists of two parts; a dose escalation part (phase I, first in- human (FIH)) and an expansion part (phase IIa). The dose escalation part has two dose escalation arms: the first arm investigates a once every 3 weeks (1Q3W) dose schedule and the second one investigates a three administrations over 4 weeks (3Q4W) dose schedule. The Expansion part of the trial, will further explore the recommended phase 2 dose of HuMax-AXL-ADC as determined in Part 1

Clinical Study Identifier: NCT02988817

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Ignace Vergote, Professor

Universitair Ziekenhuizen Leuven
Leuven, Belgium
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Ulrik Lassen, MD

Rigshospitalet, Copenhagen University Hospital
Copenhagen, Denmark
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Juanota Lopez, MD

The Royal Marsden NHS Foundation Trust
United Kingdom, United Kingdom
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