Last updated on September 2018

EMONO for the Treatment of Peripheral Neuropathic Pain


Brief description of study

To assess the effect of 3 consecutive days of one-hour administration of Nitrous Oxide/Oxygen 50%/50% (EMONO) versus placebo as Oxygen/Nitrogen 22%/78% (synthetic medical air), in add-on therapy to chronic analgesic treatments, on average pain intensity in patients with chronic peripheral neuropathic pain. A total of 250 randomised patients to be included in all the participating centres, i.e., 125 randomised patients in each of the 2 study groups treatments

Clinical Study Identifier: NCT02957851

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Caroline MAINDET, MD

CHU de Grenoble
Grenoble, France

Claire DELORME, MD

Centre Hospitalier de Bayeux
Bayeux, France

Virginie DOUSSET, MD

H pital Pellegrin
Bordeaux, France

Didier BOUHASSIRA, MD

H pital Ambroise Par
Boulogne-Billancourt, France

Jean-Bernard CAILLET, MD

Hopital Neurologique Weirthermer
Bron, France

Gisèle PICKERING, MD

Centre Hospitalier Universitaire Gabriel Montpied
Clermont-Ferrand, France

Emmanuel CHEVRILLON, MD

Clinique du Bourget
Le Bourget, France

Chantal WOOD, MD

Centre Hospitalier Universitaire Dupuytren
Limoges, France

Stéphanie RANQUE GARNIER, MD

CHU la Timone
Marseille, France

Patrick KIEFFERT, MD

Centre Hospitalier R gional de Metz-Thionville
Metz-Thionville, France

Patrick GINIES, MD

H pital Saint Eloi
Montpellier, France

Jean-Paul NGUYEN, MD

Clinique Br t ch
Nantes, France

Emmanuelle KHUN, MD

H pital Nord Laennec
Nantes, France

Thibault RIANT, MD

Nouvelles Cliniques Nantaises
Nantes, France

Eric VIEL, MD

H pital Universitaire Caremeau
Nimes, France

Alain SERRIE, MD

H pital Lariboisi re
Paris, France

Serge PERROT, MD

H pital Cochin
Paris, France

Rodrigue DELEENS, MD

Centre hospitalier Universitaire de Rouen
Rouen, France

Amar BOUGUERRA, MD

Clinique IRIS Saint-Priest
Saint-Priest, France

Thomas TOLLE, MD

Neurologische Klinik Klinikum rechts der Isar
Munchen, Germany

Clémence DAL-COL, Md

Centre Hospitalier Regional Universitaire - H pital Jean-Minjoz
Besançon, France

Claudia SOMMER, MD

Neurologische Klinik Universit tsklinikum
Würzburg, Germany